Patrick Deck

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Lipidated peptides and their neolipoprotein derivatives are efficient tools for the investigation of biological processes in molecular detail. These compounds are often acid- and base-labile, and their synthesis requires the use of a combination of blocking groups that can be removed under very mild conditions. In this article we demonstrate that the Boc(More)
The authors report their preliminary experience concerning the endovascular treatment of ruptured subarachnoid aneurysms during the acute phase in 9 patients. The endovascular approach was only used in Hunt and Hess grade IV or V patients, as an alternative to surgical clipping and in cases considered technically difficult for surgery (extremity of the(More)
Lipid-modified proteins play decisive roles in important biological processes such as signal transduction, organisation of the cytoskeleton and vesicular transport. Lipidation of these proteins is essential for correct biological function. Among the modifications with lipids, prenylation and myristoylation are well understood. However, the machinery of(More)
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