Patrick D. Allen

Learn More
Cystic fibrosis (CF) is caused by mutations in the gene that encodes the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel. In humans and pigs, the loss of CFTR impairs respiratory host defenses, causing airway infection. But CF mice are spared. We found that in all three species, CFTR secreted bicarbonate into airway surface liquid.(More)
This paper describes a methodology for developing combat simulations that may be readily tailored to specific study issues, and structured so as to treat both qualitative and quantitative variables using the natural language of military planners. The methodology was developed for the RAND Strategy Assessment System (RSAS) and exploits a new programming(More)
  • 1