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Epidermal growth factor receptor (EGFR) signaling is fundamentally important for tissue homeostasis through EGFR/ligand interactions that stimulate numerous signal transduction pathways. Aberrant EGFR signaling has been reported in inflammatory and malignant diseases, but thus far no primary inherited defects in EGFR have been recorded. Using whole-exome(More)
Although it is known that reproducibility of ambulatory blood pressure (BP) is superior to office BP in middle-aged subjects, little is known in older age groups. Hence, we compared the long-term reproducibility of ambulatory and office BP readings in subjects over the age of 75 years. A cohort of 72 subjects 75-90 years of age (mean, 82 years at baseline)(More)
Erlang is well suited as a platform for modeling neural dynamics and development. We overview similarities between neural architecture and language paradigms in Erlang, specifically functional programming, message passing, distributed computing and concurrency. We present examples of using Erlang to model neural dynamics and development respectively.(More)
implanted due to continued risk of arrhythmia from electrolyte loss from the ileostomy. The QTc came down to 454ms and BNP fell to 179pg/ml at discharge. QT prolongation is the surface ECG manifestation of abnormal repolarisation of myocardial cells due to problems with cellular ion channels. The disorder is classified as either congenital or acquired.(More)
Studies on piglets have shown that cranial bioimpedance (Z) measurements correlate well with invasively measured intracranial pressure (ICP). We have tested the feasibility of collecting transcranial impedance from a clinical device for measuring whole-body water content (ImpediMed SFB7). In the clinical study, 50 normal healthy volunteers had transcranial(More)
Atomic hydrogen exists ubiquitously in graphene materials made by chemical methods. Yet determining the effect of hydrogen on the electrochemical performance of graphene remains a significant challenge. Here we report the experimental observations of high rate capacity in hydrogen-treated 3-dimensional (3D) graphene nanofoam electrodes for lithium ion(More)
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