Patrick A. Costigan

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OBJECTIVES To identify the determinants of self-report mobility measures in people with knee osteoarthritis (OA) and to compare self-report measures with physical performance. DESIGN Cross-sectional, prospective. SETTING Motor performance laboratory and human mobility research center. PARTICIPANTS A convenient sample of 54 participants with medial(More)
BACKGROUND To determine the effects of changing the natural foot progression angle during gait (internal and external foot rotation) on the knee's adduction moment, lateral-medial shear force, and the ratio of medial-lateral hamstring muscle activation in those with signs of knee osteoarthritis and a matched healthy control group. METHODS Twelve subjects(More)
Understanding joint kinetics during activities of daily living furthers our understanding of the factors involved in joint pathology and the effects of treatment. In this study, we examined hip and knee joint kinetics during stair climbing in 35 young healthy subjects using a subject-specific knee model to estimate bone-on-bone tibiofemoral and(More)
The extent to which errors in predicting body segment parameters (SP) influence biomechanical analysis of human motion is unclear. Therefore, the current study quantitatively evaluated the differences in SP estimates using literature predictive functions and computed the effect of SP variation on the kinetic output of walking. For a group of 15 young males,(More)
BACKGROUND AND PURPOSE This cross-sectional study evaluated the relative contributions of psychosocial and mechanical variables to physical performance measures in people with knee osteoarthritis (OA). SUBJECTS Fifty-four subjects (age, in years: mean=68.3, SD=8.7, range=50-87) with radiographically confirmed knee OA were included in this study. METHODS(More)
Osteoarthritis of the knee is associated with deformities of the lower limb and malalignment of the limb segments. Pathogenetic relationships between the two are poorly understood. Alignment was studied by standardized radiography in 167 symptomatic Canadian osteoarthritis patients, and compared with 119 healthy adult volunteers. In healthy adults overall(More)
OBJECTIVE Gait biomechanics (knee adduction moment, center of pressure) and static alignment were investigated to determine the mechanical effect of foot orthoses in people with medial compartment knee osteoarthritis. DESIGN Repeated measures design in which subjects were exposed to three conditions (normal footwear, heel wedge and orthosis) in random(More)
BACKGROUND Pain experienced by people with knee osteoarthritis is related to psychosocial factors and damage to articular tissues and/or the pain pathway itself. Mechanical factors have been speculated to trigger this pain experience; yet mechanics have not been identified as a source of pain in this population. The purpose of this study was to identify(More)
OBJECTIVE To determine the reliability and validity of ankle proprioceptive measures. DESIGN Reliability was assessed between test occasions. Construct validity was addressed by the ability of measures to differentiate among groups. SETTING Laboratory of an educational institution. PARTICIPANTS Eight healthy adults were recruited into each of 3(More)
There is evidence that joint load is a factor in the development of osteoarthritis (OA) and, while altered gait profiles have been linked with OA, it is unknown if abnormal gait is a cause or effect of the disease. While the knee's adduction moment has been implicated in the development and progression of knee OA, it is also known that shearing forces are(More)