Patricia Wood

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We have developed a method for visualizing Escherichia coli cells that are exposed to tetracycline in a biofilm, based on a previous report that liposomes containing the E. coli TetR(B) protein fluoresce when exposed to this antibiotic. By our method, cells devoid of TetR(B) also exhibited tetracycline-dependent fluorescence. At 50 microg of tetracycline(More)
Aspartate aminotransferases have been cloned and expressed from Crithidia fasciculata, Trypanosoma brucei brucei, Giardia intestinalis, and Plasmodium falciparum and have been found to play a role in the final step of methionine regeneration from methylthioadenosine. All five enzymes contain sequence motifs consistent with membership in the Ia subfamily of(More)
We report the discovery of a new M9.0 dwarf at only 8.2 pc, which we identified in our search for nearby ultracool dwarf (I−J 3.0, later than M8.0) in the DENIS database. We measure a very high proper motion of 2.5 arc-sec/yr. The PC3 index measured from its low-resolution spectrum gives a spectrophotometric distance of 8.2 pc. This makes it the third(More)
I am active in professional societies and continue to coordinate a number of society award nominations on behalf of my scientific colleagues. I review ~25–30 papers for scientific journals each year as well as research grants for various organizations and participate on various review panels. The Brown group carries out fundamental research in molecular(More)
I am active in professional societies and coordinate a number of society award nominations for scientific colleagues. I am Associate Editor of the Biophysical Journal and review ~20–30 scientific papers each year as well as research grants for various organizations and participate on various review panels. Award of Biophysical Society-3 nominations (all(More)
Erythrocyte structure and function depend upon interactions between proteins in and associated with the membrane, centered around band 3. This protein harbours physiological removal signals and, as a main component of the links between the cytoskeleton and the lipid bilayer, plays a central role in deformability. Also, as a binding partner of hemoglo-bin(More)
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