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Type-2 fuzzy sets are used for modeling uncertainty and imprecision in a better way. These type-2 fuzzy sets were originally presented by Zadeh in 1975 and are essentially "fuzzy fuzzy" sets where the fuzzy degree of membership is a type-1 fuzzy set. The new concepts were introduced by Mendel and Liang allowing the characterization of a type-2 fuzzy set(More)
In the disease cystic fibrosis (CF), the most common mutation delF508 results in endoplasmic reticulum retention of misfolded CF gene proteins (CFTR). We show that the alpha-1,2-glucosidase inhibitor miglustat (N-butyldeoxynojirimycin, NB-DNJ) prevents delF508-CFTR/calnexin interaction and restores cAMP-activated chloride current in epithelial CF cells.(More)
A review of the applications of interval type-2 fuzzy logic in intelligent control has been considered in this paper. The fundamental focus of the paper is based on the basic reasons for using type-2 fuzzy controllers for different areas of application. Recently, bio-inspired methods have emerged as powerful optimization algorithms for solving complex(More)
A polyphosphoinositide phospholipase C has been identified in highly purified plasma membranes from shoots and roots of wheat seedlings. The enzyme preferentially hydrolysed phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate and had a different phosphoinositide substrate profile from soluble phospholipase C. The enzyme activity was(More)
Polyphosphoinositide-specific phospholipase C activity was present in plasma membranes isolated from different tissues of several higher plants. Phospholipase C activities against added phosphatidylinositol 4-phosphate (PIP) and phosphatidylinositol 4,5-bisphosphate (PIP(2)) were further characterized in plasma membrane fractions isolated from shoots and(More)