Patricia M Mahoney

Learn More
Mg metal and its alloys have promise as a biocompatible, degradable biomaterials. This work evaluates the potential of in vitro cell culture work with osteoblast-like cells on Mg based materials, and investigates cell differentiation and growth on Mg alloyed with various non-toxic or low-toxicity elements. Mg based substrates support the adhesion,(More)
The hard tissues of the temporomandibular joint (TMJ) can be assessed through radiographic imaging to provide information to assist in diagnosis and treatment. However, the quality of information gathered from such imaging is often less than desired due to the small size of the TMJ, the widely varying fossa and condylar morphology, and the surrounding dense(More)
Reconstituted keratin-hydroxyapatite (K-HA) composites have shown potential as nonload-bearing bone graft substitute material. This in vivo study investigated the bone regeneration response of keratin plus 40% HA composite materials in comparison to collagen counterparts and an unfilled defect site. The implantation site was a noncritical size defect(More)
Monocationic 99mTc-nitrido complexes of a variety of diphosphine ligands have been prepared and the in vivo distribution of such cations has been examined in Sprague-Dawley rats. These complexes show initially high myocardial uptake with subsequent wash-out in this animal model. The lack of myocardial retention can be attributed to the facile in vivo(More)
Mast cell populations in the vaginal cul-de-sac of female brushtail possums do not appear to be related to microbial invasion but changes in their density occur at oestrus, indicating a hormonal influence. The present study examined the effect of treatment with oestradiol on microflora and on mast cell numbers and their spatial location in cul-de-sac tissue(More)
Mast cells are typically associated with biological responses to intracellular parasitic or bacterial invasion in gut and pulmonary tissues. Large numbers of these cells are present in the vaginal cul-de-sac, a component of the reproductive tract in female brushtail possums (Trichosurus vulpecula). The presence of mast cells in this area may reflect(More)
Reconstituted keratin has shown promise as an orthopaedic biomaterial. This in vivo study investigates the biological response of composite materials prepared from reconstituted keratin containing a high content of hydroxyapatite (HA) (40 wt % HA), implanted for up to 18 weeks in the long bones of sheep. Keratin-HA composites were compared with a(More)
  • 1