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BACKGROUND Reliable information about the prevalence of hypertension in different world regions is essential to the development of national and international health policies for prevention and control of this condition. We aimed to pool data from different regions of the world to estimate the overall prevalence and absolute burden of hypertension in 2000,(More)
BACKGROUND Results of previous randomised trials have shown that interventions that lower LDL cholesterol concentrations can significantly reduce the incidence of coronary heart disease (CHD) and other major vascular events in a wide range of individuals. But each separate trial has limited power to assess particular outcomes or particular categories of(More)
OBJECTIVE To assess the effects of selective cyclo-oxygenase-2 (COX 2) inhibitors and traditional non-steroidal anti-inflammatory drugs (NSAIDs) on the risk of vascular events. DESIGN Meta-analysis of published and unpublished tabular data from randomised trials, with indirect estimation of the effects of traditional NSAIDs. DATA SOURCES Medline and(More)
How did the study come about? Ireland shares with other developed countries the prospect of rapid and sustained population ageing. The age distribution of the Irish population is undergoing a dramatic change at present and this trend is predicted to continue into the future. 1 People are living longer, and older persons represent a larger proportion of the(More)
Traditional collaborative filtering generates recommendations for the active user based solely on ratings of items by other users. However, most businesses today have item ontologies that provide a useful source of content descriptors that can be used to enhance the quality of recommendations generated. In this article, we present a novel approach to(More)
BACKGROUND Parental obesity is a predominant risk factor for childhood obesity. Family factors including socio-economic status (SES) play a role in determining parent weight. It is essential to unpick how shared family factors impact on child weight. This study aims to investigate the association between measured parent weight status, familial(More)
Upregulation of xCT, the inducible subunit of a membrane-bound amino acid transporter, replenishes intracellular glutathione stores to maintain cell viability in an environment of oxidative stress. xCT also serves as a fusion-entry receptor for the Kaposi's sarcoma-associated herpesvirus (KSHV), the causative agent of Kaposi's sarcoma (KS). Ongoing KSHV(More)
Macrophages are an important source of inflammatory cytokines generated during the innate immune response,but in the microenvironment of certain tumors,macrophages promote tumor progression through their preferential secretion of cytokines that support tumor cell growth and suppress antitumoral immune responses. KSHV is the causative agent of KS and(More)
  • James W. Neuliep, Steven A. Beebe, +20 authors Prahalad Sooknanan
  • 2009
In this fully updated Fifth Edition of Intercultural Communication, author James W. Neuliep provides a clear contextual circular model for examining communication within cultural, micro-cultural, environmental, socio-relational, perceptual contexts, and verbal and nonverbal codes. The text begins with the broadest context; the cultural component of the(More)