Patricia Hess

Learn More
The c-Jun NH(2)-terminal kinase (JNK) signaling pathway is induced by cytokines and stress stimuli and is implicated in cell death and differentiation, but the specific function of this pathway depends on the cell type. Here we examined the role of JNK1 and JNK2 in CD8(+) T cells. Unlike CD4(+) T cells, the absence of JNK2 causes increased interleukin(More)
even when did not believe in myself and my family for an upbringing that encouraged me to follow my dreams and whose constant support helped me achieve this goal. ACKNOWLEDGMENTS I gratefully thank Bob Lahue for being all the things that a mentor should be: a knowledgeable and talented scientist, a patient and caring teacher and, when he needed to be, an(More)
Sixty % of clones isolated from HeLa cells treated with toxic concen trations of a methylating carcinogen showed increased resistance to the cytotoxicity of A'-methyl-A'-nitrosourea. D,7 values were 6-to 100-fold higher than in the parental cell population. The absence of detectable levels of the repair enzyme 06-methylguanine-DNA methyltransferase(More)
  • Necrosis M D Thesis, Jh Boss, Koren G, Rosenmann E Semiquantitative, Koren, Appelbaum D Hasin +45 others
  • 2006
determination of liver specific antigens in the urine of rats with toxic necrosis. Prevention of myocardial damage by very early treatment with intravenous streptokinase. New Engl. following reperfusion with streptokinase (Bezold-Jarisch reflex)-a sign of coronary thrombolysis and myocardial salvage. Gotsman MS. Importance of early initiation of intravenous(More)
The mutant mouse strain Mpv17-/-, carries a retroviral germline integration that inactivates the Mpv17 gene. Mpv17-deficient mice develop progressive glomerulosclerosis and sensineural deafness at early age. Characteristic basement membrane alterations are found in both sites of pathology. Mpv17 is a peroxisomal protein involved in the metabolism of(More)
  • 1