Patricia Hernandez

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Most combinatorial optimization problems cannot be solved exactly. A class of methods, called metaheuristics, has proved its eeciency to give good approximated solutions in a reasonable time. Cooperative metaheuristics are a subset of metaheuristics, which implies a parallel exploration of the search space by several entities with information exchange(More)
Biomarker detection is one of the greatest challenges in Clinical Proteomics. Today, great hopes are placed into tandem mass spectrometry (MS/MS) to discover potential biomarkers. MS/MS is a technique that allows large scale data analysis, including the identification, characterization, and quantification of molecules. Especially the identification process,(More)
The identification and characterization of peptides from tandem mass spectrometry (MS/MS) data represents a critical aspect of proteomics. Today, tandem MS analysis is often performed by only using a single identification program achieving identification rates between 10-50% (Elias and Gygi, 2007). Beside the development of new analysis tools, recent(More)
In this study, gamma irradiation induced degradation of orange peels (OP) was investigated. The lignocellulosic biomass degradation was carried out at doses of 0 (control), 600, 1800 and 3500 kGy using a Co-60 gamma radiation source. The samples were tested for total and reducing sugars. The concentrations of total sugars ranged from 0.530 g • g −1 in(More)
BACKGROUND Osteoarthritis of the knee is a major cause of disability among adults. Electro-acupuncture is considered a potentially useful treatment for osteoarthritis. The purpose of this study is to assess the efficacy of electro-acupuncture on pain control, pain perception, plasma cortisol and beta-endorphin levels, patient-perceived quality of life, and(More)
Understanding and emulating human creativity is a key factor when developing computer based algorithms devoted to art. This paper presents a new evolutionary approach to art and creativity aimed at comprehending human principles and motivations, behaviors and procedures from an evolutionary point of view. The results, and the collective artwork described,(More)
2. These guidelines are considered as a joint publication due to the close cooperation leading to extensive comments, suggestions and insights provided by Patricia Hernández, Nathalie Van de Maele, Cornelis van Mosseveld and other members of the WHO NHA Team. 3. responsible for health accounts at the Swiss Federal Statistical Office) and Moulay Driss(More)