Patricia Garrido Castro

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We describe the QUaD experiment, a millimeter-wavelength polarimeter designed to observe the cosmic microwave background (CMB) from a site at the South Pole. The experiment comprises a 2.64 m Cassegrain telescope equipped with a cryogenically cooled receiver containing an array of 62 polarization-sensitive bolometers. The focal plane contains pixels at two(More)
MLL/AF4 and AML/MTG8 represent two leukemic fusion genes, which are most frequently found in infant acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML), respectively. We examined the influence of MLL/AF4 and AML1/MTG8 fusion genes on the expression of TERT coding for the telomerase protein subunit, and subsequently telomerase activity in(More)
  • Quad Collaboration, M L Brown, +7 authors E Y S Wu
  • 2009
We present an improved analysis of the final dataset from the QUaD experiment. Using an improved technique to remove ground contamination, we double the effective sky area and hence increase the precision of our CMB power spectrum measurements by ∼ 30% versus that previously reported. In addition, we have improved our modeling of the instrument beams and(More)
SiRNA molecules represent promising therapeutic molecules, e.g. for cancer therapy. However, efficient delivery into tumor cells remains a major obstacle for treatment. Here, we describe a liposomal siRNA carrier system for targeted delivery of siRNA to CD33-positive acute myeloid leukemia cells. The siRNA is directed against the t(8;21) translocation(More)
We report results from the second and third seasons of observation with the QUaD experiment. Angular power spectra of the cosmic microwave background are derived for both temperature and polarization at both 100 GHz and 150 GHz, and as cross-frequency spectra. All spectra are subjected to an extensive set of jackknife tests to probe for possible systematic(More)
We propose an estimator for the trispectrum of a scalar random field on a sphere, discuss its geometrical and statistical properties, and outline its implementation. By estimating the trispectrum of the 4 year COBE-DMR data (in HEALPix pixelization) we find new evidence of a non-Gaussian signal associated with a known systematic effect. We find that by(More)
We present a search for non-Gaussianity in the WMAP first-year data using the twopoint correlation function of maxima and minima in the temperature map. We find evidence for non-Gaussianity on large scales, whose origin appears to be associated with unsubstracted foregrounds, but which is not entirely clear. The signal appears to be associated most strongly(More)
We report on investigations of the power of next generation cosmic microwave background and large scale structure surveys in constraining the nature of dark energy through the cross-correlation of the Integrated Sachs Wolfe effect and the galaxy distribution. First we employ a signal to noise analysis to find the most appropriate properties of a survey in(More)
By correctly identifying the role of central extension in the centrally extended Heisenberg algebra h, we show that it is indeed possible to construct a Hopf algebraic structure on the corresponding enveloping algebra U(h) and eventually deform it through Drinfeld twist. This Hopf algebraic structure and its deformed version UF (h) are shown to be induced(More)