Patricia E. Roth

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3'2b transgenic mice have a severe B cell defect, apparently caused by strong feedback inhibition of endogenous H-gene rearrangement coupled with an inability of 3,2b to provide the survival/matu-ration functions of/~. A unique 3,2b transgenic line, named the C line, was found to permit B cell development. When the C line is crossed with a #-membrane(More)
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