Patricia Baier

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PURPOSE Approximately 20% to 30% of patients with curatively resected, node-negative (pN0) colorectal cancer die of tumor recurrence, which can be caused by minimal residual disease. To identify patients with an increased risk of tumor recurrence and evaluate the prognostic value of cytokeratin-20 (CK-20), we detected CK-20-positive cells in(More)
Ultrasound has become indispensable in prenatal diagnosis. Ultrasound training, however, still lacks proper quality assessment and control. Moreover, most fetal anomalies which must be diagnosed during pregnancy are extremely rare. Ultrasound simulators could provide an opportunity to overcome this dilemma. This review summarizes the potential benefits of(More)
In 2 cases of tuberous sclerosis complex (TSC), a disseminated distribution of atypical cells throughout the white matter and cortex of the telencephalon has been found. No cortical tubera were observed. In 1 of the cases, ventricular wall tumors (giant astrocytomas) were present. Stripes and candle guttering excrescences of groups of atypical cells(More)
OBJECTIVES We aimed to find answers to the following questions: What are the technical and biological prerequisites for easily obtainable three-dimensional (3D) images? What are the visualization rates for various fetal organ systems? What is the potential for assessing fetal malformations? What are the psychological effects of 3D imaging on the expectant(More)
Amniotic fluid contains a heavily glycosylated pregnancy-related isoform of fibronectin (fFN), which can be detected using FDC-6, a monoclonal antibody directed against a novel epitope specific to fFN. It has been identified in the amniotic fluid in various concentrations throughout the different pregnancy periods and is localised at the interface of the(More)
PURPOSE Although ultrasound examination became almost indispensable in prenatal diagnosis as well as in gynecological examination, there are still a lot of deficits in the quality management of medical education. We present a "ultrasound simulation system", that makes it possible to simulate a complete ultrasound examination. The system is able to simulate(More)
Last years evaluation of fluorescence-in-situ-hybridization (FISH) allowed detection of chromosomal abnormalities by using DNA probes, binding to chromosomes in the nucleus. Because it is possible to directly examine interphase nuclei, FISH-technique, in contrast to traditional cytogenetic analysis has the advantage of small loss of time in case of urgent(More)
9517 Background: The presence of cytokeratin (CK) positive cells in bone marrow of breast cancer patients is correlated with worse clinical outcome. Therefore these cells were suggested to be derived from the primary tumor and are considered to represent an early metastatic tumor cell spread. Presence of these cells may be associated with highly aggressive(More)
Roots of Wilbrandia ebracteata Cogn., Cucurbitaceae, used in folk medicine for treatment of rheumatic disease, are rich in cucurbitacins. Dihydrocucurbitacin B is the most abundant cucurbitacin while cucurbitacin B is a minor component. A reverse-phase HPLC system was developed for simultaneous quantitative assay of these cucurbitacins in the roots. The(More)
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