Patricia Abrudan

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BACKGROUND mRNA polyadenylation, the addition of a poly(A) tail to the 3'-end of pre-mRNA, is a process critical to gene expression and regulation in eukaryotes. To understand the molecular mechanisms governing polyadenylation and other relevant biological processes, it is important to identify these poly(A) tails accurately in transcriptome sequencing data(More)
In this poster we will describe SCOPE: a tool for the identification and removal of homopolymer sequences embedded in sequenced mRNA transcript fragments as a result of the Eukaryotic polyadenylation process, allowing for the identification and cleaning of next generation sequence transcriptome data of fragments added by post-transcriptional processes. By(More)
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