Patrícia Trevisan

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BACKGROUND Chromosomal abnormalities (CAs) are an important cause of congenital heart disease (CHD). OBJECTIVE Determine the frequency, types and clinical characteristics of CAs identified in a sample of prospective and consecutive patients with CHD. METHOD Our sample consisted of patients with CHD evaluated during their first hospitalization in a(More)
BACKGROUND Congenital heart disease (CHD) is a serious threat to public health. Despite this, its etiology is poorly understood and few cardiac teratogens have been defined. The aim of the present study was to identify gestational and family risk factors for CHD in a sample of patients from a pediatric hospital in southern Brazil. METHODS A prospective(More)
OBJECTIVE To evaluate lung function and respiratory muscle strength in the postoperative period and investigate the effect of inspiratory muscle training on measures of respiratory muscle performance in patients undergoing coronary artery bypass grafting. METHODS A randomized study with 47 patients undergoing coronary artery bypass grafting with(More)
OBJECTIVE To review the relationship between congenital heart defects and chromosomal abnormalities detected by the karyotype. DATA SOURCES Scientific articles were searched in MEDLINE database, using the descriptors "karyotype" OR "chromosomal" OR "chromosome" AND "heart defects, congenital". The research was limited to articles published in English from(More)
OBJECTIVE Investigate the frequency of 22q11 deletion syndrome among patients with complex congenital heart disease. METHODS A prospective and consecutive cohort of patients with complex heart defects was evaluated in their first hospitalization at a cardiac intensive care unit of a pediatric hospital. For each patient a protocol of demographic and(More)
BACKGROUND Trisomy 18 or Edwards syndrome is a chromosomal abnormality characterized by a broad clinical picture and a limited survival. More than 130 different abnormalities have been described in these patients-among them are neural tube defects. METHODS We verified the frequency and types of major neural tube defects observed among patients with(More)