Pat Tso

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N-acylphosphatidylethanolamines (NAPEs) are a relatively abundant group of plasma lipids of unknown physiological significance. Here, we show that NAPEs are secreted into circulation from the small intestine in response to ingested fat and that systemic administration of the most abundant circulating NAPE, at physiologic doses, decreases food intake in rats(More)
Chemicals. HPLC grade organic solvents including methanol, acetonitrile, chloroform and methylene chloride were purchased from Sigma/Aldrich (St. Louis, MO). N-Palmitoylethanolamine (PEA), N-stearoylethanolamine (SEA), heptadecanoyl chloride, triethylamine and butylated hydroxytoluene (BHT) were also purchased from Sigma/Aldrich (St. Louis, MO).(More)
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