Pascale Olivier-Abbal

Learn More
Our aim was to describe all serious cutaneous adverse drug reactions (ADRs) spontaneously reported in France for all oral protein kinase inhibitors, their characteristics and whether they were labeled (reported in the Summary of Product Characteristics) or not. We performed a retrospective observational study in the French PharmacoVigilance Database,(More)
Antineoplastic drugs are one of the pharmacological classes more frequently involved in occurrence of “serious” adverse drug reactions. However, few epidemiological data are available regarding the preventability of adverse drug reactions with ambulatory cancer chemotherapy. We assessed the rate and characteristics of “preventable” or “potentially(More)
PURPOSE The objective of our study was to determine the nature of scientific evidence leading to drug withdrawal for safety reasons in France (between 2005 and 2011). METHODS Drugs (i.e., active ingredients) withdrawn were identified from the Web site of the French Health Products Agency. Additional information allowed us to classify these withdrawals(More)
To the Editor: We present a case of a healthy young man who had an acute coronary syndrome 2 days aft er using oxymetazoline. Th e patient was a white man in his early 30s without a medical history who was suff ering from acute nasal congestion with rhinorrhea. He was treated with oral pseudoephedrine, paracetamol, and triprolidine for 5 days and then nasal(More)
Thalidomide and lenalidomide are structural analogs and immunomodulatory drugs. Lenalidomide appears to have a different safety profile than thalidomide and could be less toxic, and as far as we know, we did not found any study comparing their safety profile. The objective of our study was to review and compare serious adverse drug reactions (SADRs) of(More)
Studies have shown that omega-3 polyunsaturated fatty acids (PUFAs) are associated with brain, cardiovascular, and immune function, as well as physical performance and bone health in older adults. So far, few studies have investigated the associations between PUFA status and performance-based tests of physical function. The objective of this study was to(More)
In recent years, the preventability of adverse drug reactions (ADRs) has gradually gained ground as an additional criterion for assessing drug-related risk, alongside seriousness, causality mechanism of action or frequency. However, the definition of preventability itself remains a concept that needs to be defined clearly so as to compare study results.(More)
  • 1