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  • Thierry Bordet, Bruno Buisson, +15 authors Rebecca M. Pruss
  • Medicine, Chemistry
  • The Journal of pharmacology and experimental…
  • 2007 (First Publication: 1 August 2007)
  • Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive death of cortical and spinal motor neurons, for which there is no effective treatment. Using aContinue Reading
  • Francisco Santos Schneider, Dung Le Nguyen, +9 authors Franck Molina
  • Biology, Medicine
  • PLoS neglected tropical diseases
  • 2014 (First Publication: 1 April 2014)
  • BACKGROUND The snake Bothrops atrox is responsible for the majority of envenomings in the northern region of South America. Severe local effects, including hemorrhage, which are mainly caused byContinue Reading
  • John J. Flanagan, Akram Arjomandi, +6 authors Steven R. Binder
  • Chemistry, Medicine
  • Journal of immunological methods
  • 2014 (First Publication: 1 April 2014)
  • Haptoglobins (HPs) are alpha 2-globulin proteins that bind free hemoglobin in plasma to prevent oxidative damage. HPs are produced as preproteins that are proteolytically cleaved in the ER into alphaContinue Reading
  • Camila Dias-Lopes, Liza Felicori, +7 authors Carlos Chávez-Olórtegui
  • Medicine, Biology
  • Vaccine
  • 2014 (First Publication: 1 April 2014)
  • We report the production of a neutralizing monoclonal antibody able to recognize the venoms of three major medically important species of Loxosceles spiders in Brazil. The mAb was produced byContinue Reading