Pascal Nussbaum

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To determine the effects of methyldopa on renal function, clearance studies were performed on hypertensive subjects during sustained steady-state water diuresis. The data reveal an acute fall in glomerular filtration rate and sodium clearance, whereas renal blood flow was unchanged. The antinatriuresis was the result of decreased filtration of sodium and(More)
IL-10 plays an important role in the control of immune reactions during systemic infection. Here, IL-10 serum levels were investigated in patients after BMT. The IL-10 levels correlated with the clinical course of the patients and with serum levels of C-reactive protein (CRP) and neopterin (NP). A total of 26 patients with AML (7), ALL (12), CML (2), NHL(More)
—A 100 100 pixel analog very large scale integration retina is proposed to extract the magnitude and direction of spatial gradients contained in sensed images. The retina implements in a massively parallel fashion, at pixel level, an algorithm based on the concept of steerable filters to compute the gradients. An output rate of up to 1000 frames per second(More)
A haloperidol-treated patient with chronic schizophrenia had a near-arrhythmic circadian rest-activity cycle, whereas rhythms of 6-sulphatoxy-melatonin and core body temperature were of normal amplitude and phase-advanced. Sleep electroencephalography measured throughout a 31-h 'constant-bedrest' protocol revealed a phase-delayed sleep-wake propensity(More)
We studied 11 patients with stable multiple sclerosis (MS) with major depression in terms of response to Sertraline at 100 mg q.d. in an open label trial. Patients were evaluated with self assessment measurements (Carroll scale) prior to and during treatment. Only one patient discontinued the drug during the three month treatment trial, and this was due to(More)
The crossbreeding between advanced microprocessor design and Field Programmable Gate Arrays (FPGAs) has produced the Field Programmable Processor Array, code named FPPA. The first integrated version has been targeted for low power consumption parallel processing. The FPPA is composed of a 10×10 array of RISC microcontrollers offering up to 500 MIPS at 5 MHz(More)
In order to master the growing complexity of analogue electronic systems, modelling and simulation of analogue hardware at various levels is absolutely necessary. This paper presents an original modelling method based on the graphical description of analogue electronic functional blocks. This method is intended to be automated and integrated into a design(More)