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Extracellular recordings of 209 neurons were obtained with carbon fiber-containing multibarrel micropipettes. The cells were isolated in the primary somatosensory cortex of cats anesthetized with barbiturate and classified according to the nature of their response to natural stimuli, the nature of the surrounding multiunit responses to the same stimuli, the(More)
Slow and fast pyramidal tract cells (Pt cells) from the cat motor cortex were identified antidromically and injected with horseradish peroxidase (HRP). The axonal collaterals of these cells were mapped following HRP histochemistry with benzidine di-hydrochloride. All cells, slow or fast, show a similar arrangement of their collaterals. A proximal axonal(More)
Extracellular recordings of 105 neurones in the cat's somatosensory thalamus were obtained with carbon fibre-containing multibarrel micropipettes. The responses of cells to natural stimulation of cutaneous or deep structures were characterized and the responses to electrical stimulation of primary somatosensory cortex were determined. Receptive fields were(More)
The intracortical arborizations of thalamocortical fibers arising from the ventroposterolateral (VPL) nucleus in the cat were studied following intra-axonal injections of horseradish peroxidase (HRP). The axons were impaled 1.5 to 3 mm below the surface of the cortex, identified electrophysiologically by stimulating the VPL nucleus and functionally by(More)
In deeply anesthetized cats the temporal characteristics of ventro-lateral (thalamic) excitatory postsynaptic potentials (EPSPs) induced in pyramidal tract cells were studied with an averaging technique. Stimulation of the ventrolateral thalamus induced EPSPs in all pyramidal tract neurons at latencies of 1-5 ms. It was found that there was a positive(More)
The intracortical arborizations of neurons from the ventroposterolateral thalamic nucleus (VPL) in the cat were studied by intraaxonal injections of horseradish peroxidase (HRP) following identification of their receptive fields. In the primary somatic sensory cortex (SI) VPL cells terminated in different cytoarchitectonic areas according to their receptive(More)
Responses evoked in neurons of rat sensorimotor cortex upon stimulation of the pyramidal tract and ipsilateral cerebral peduncle were analysed using intracellular recording. Neurons responding antidromically to pyramidal tract stimulation (PT cells) and neurons failing to respond antidromically but exhibiting orthodromic responses were both stained by(More)
Extracellular and intracellular recordings of corticothalamic (CT) cells were performed in the primary somatosensory cortex of the cat. CT neurons were antidromically activated by electrically stimulating the ventroposterior lateral (VPL) nucleus of the thalamus and were classified into two types according to their physiological properties. Type 1 had no(More)
This study evaluated an inference-based approach (IBA) to the treatment of obsessive-compulsive disorder (OCD) by comparing its efficacy with a treatment based on the cognitive appraisal model (CAM) and exposure and response prevention (ERP). IBA considers initial intrusions in OCD (e.g. "Maybe the door is open", "My hands could be dirty") as idiosyncratic(More)