Partha Pal Chaudhuri

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Metacyclic (stationary) and logarithmic (log) forms of promastigotes of Leishmania donovani and Leishmania major were characterized in several ways. The highly active metacyclic forms were larger with more protein and less carbohydrate. The flagellum increased in length 2.4 times in L. major as compared to 1.8 times in L. donovani. Resistance to(More)
During a 2-year study, Cryptosporidium oocysts were detected in 32 (5.6%) of 566 hospitalized paediatric diarrhoea cases and 2 (1.2%) of 167 non-diarrhoeic individuals. Cryptosporidium was the sole pathogen detected in 17 (3.0%) of the 32 positive cases; in the other 15 it occurred in combination with one or more other established enteropathogen(s). The(More)
The crude soluble antigens (CSA) of Giardia lamblia trophozoites and their analytically purified fractions were characterized biochemically and immunologically to determine the most immunogenic fraction and its localization on the parasite. Both Sephacryl S-300 column chromatography and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE)(More)
Electrophoretic mobility patterns of six enzymes, viz. alkaline phosphatase E.C., acid phosphatase E.C., malic enzyme E.C., phosphoglucomutase E.C., isocitrate dehydrogenase E.C., glucose-6-phosphate dehydrogenase E.C. of two axenically cultured human Giardia lamblia isolated from India (PD-1 and PD-2)(More)
Six monoclonal antibodies (MAbs) were produced against a highly immunogenic fraction derived by the chromatographic separation of the soluble preparation of axenic Entamoeba histolytica (strain NIH:200) trophozoites. Isotype characterization of the six MAbs revealed that four belonged to the IgM class and one each to the IgG1 and the IgG2a subclasses. The(More)
O f the 29 I V D U with an t i -HCV, 12 ( inc lud ing the t h r e e c o m p a n i o n s of the a n t i H C V pos i t ive fema le p a r t n e r s ) had ra i sed levels of a l an ine a m i n o t r ans fe rase . O u r d a t a sugges t tha t sexual t r ansmis s ion is c o m m o n and tha t f e m a l e p a r t n e r s of I V D U are a g r o u p at r isk for H C(More)
A cDNA expression library of Entamoeba histolytica was screened with antiserum to native amoebic collagen binding proteins (CBPs), and two clones C13 and C7 which partially encode for the 30 kDa CBP were obtained. The sequenced clones were 90% homologous. C7 had a 69 bp deletion at the 5' end that is present in C13 and encodes for a Glu-Cys-Lys rich region(More)
The roles of circulating anti-Giardia IgM and IgG antibodies were assayed by the Enzyme linked immunosorbent assay (ELISA) using axenic Giardia lamblia whole trophozoites as antigen for routine serodiagnosis of Giardia infection. Detection of anti-Giardia IgM antibody was found to be useful in the early detection of symptomatic giardiasis, whereas IgG(More)
MicroRNAs (miRNAs) originally an unappreciated class of small ribonucleic acids (RNAs) were diagnosed as moderate biological modifiers. Over the years rigorous research on microRNAs established them as a powerful regulator of various cellular processes like occurrence of different diseases. In this paper cellular automata approach is used by replacing the(More)
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