Parinaz Massoumzadeh

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The accurate determination of x-ray signal properties is important to several computed tomography (CT) research and development areas, notably for statistical reconstruction algorithms and dose-reduction simulation. The most commonly used model of CT signal formation, assuming monoenergetic x-ray sources with quantum counting detectors obeying simple(More)
Region of interest (ROI) fluoroscopic techniques have the potential for improving image quality and greatly reducing radiation dose. The utility of ROI imaging depends on the material used for the filter. Various materials for x-ray beam shaping ROI filters are evaluated using a computer simulation to determine their transmission and effect on radiographic(More)
RATIONALE AND OBJECTIVES To compare quantitative imaging parameter measures from diffusion- and perfusion-weighted imaging magnetic resonance imaging (MRI) sequences in subjects with brain tumors that have been processed with different software platforms. MATERIALS AND METHODS Scans from 20 subjects with primary brain tumors were selected from the(More)
The objective of this research was to develop and validate a custom computed tomography dose-reduction simulation technique for producing images that have an appearance consistent with the same scan performed at a lower mAs (with fixed kVp, rotation time, and collimation). Synthetic noise is added to projection (sinogram) data, incorporating a stochastic(More)
OBJECTIVES Glucose metabolism outside of oxidative phosphorylation, or aerobic glycolysis (AG), is a hallmark of active cancer cells that is not directly measured with standard (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET). In this study, we characterized tumor regions with elevated AG defined based on PET measurements of glucose and(More)
In region-of-interest (ROI) fluoroscopy, a filter is used to greatly attenuate the x-ray beam outside the ROI and digital image processing is used to equalize the displayed brightness. The method is applicable to real-time imaging procedures such as vascular interventions for which a high-quality image is essential only over an ROI (eg, near the catheter(More)
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