Paramoo Sugathan

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OBJECTIVE Hand-Foot-and-Mouth Disease (HFMD) is a mild exanthematous illness seen worldwide, affecting mainly children under ten years of age. The causative agents were initially Coxsackie virus type A 16 and related serotypes. The situation changed drastically about thirty years ago with the advent of a new aetiological agent, Enterovirus type 71 (EV 71),(More)
The management of children suffering from sickle cell disease [sickle cell anaemia (SCA) and sickle cell beta degree-thalassaemia (S beta degree-thal.)] has been the concern of all clinicians caring for these patients. Several agents have been tried for treatment, often limited by toxic side effects. Piracetam (2-oxo-l-pyrrolidine acetamide, Nootropyl), a(More)
Cutaneous larva migrans is a tropical disease that typically is acquired on exposed surfaces in patients who have been sitting or lying on moist ground or other surfaces which have been contaminated by dog or cat feces. A patient is reported who presented with typical, severely pruritic, migratory plaques after sleeping on a wet, bus station floor.
Noninvasive M mode echocardiography with Doppler recording was prospectively performed on type I diabetic recipients of pancreas-kidney (n = 20), pancreas-after-kidney (n = 2), and kidney-alone (n = 11) allografts to determine whether the return of euglycemia by pancreas transplantation in the uremic diabetic person was associated with improved cardiac(More)
STUDY OBJECTIVE To evaluate an animal model of multiple-dose activated charcoal (MDAC) therapy and correlate the pharmacokinetic properties of four drugs with the efficacy of MDAC. DESIGN Prospective, randomized, controlled, crossover design. SETTING A university animal research facility. PARTICIPANTS Seven female pigs (15 to 22 kg) with an indwelling(More)