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This paper concerns the search for optimal or nearly optimal batting orders in one-day cricket. A search is conducted over the space of permutations of batting orders where simulated annealing is used to explore the space. A non-standard aspect of the optimization is that the objective function (which is the mean number of runs per innings) is unavailable(More)
BACKGROUND Updated, robust estimates of the incidence and prevalence of rare long-term neurological conditions in the UK are not available. Global estimates may be misrepresentative as disease aetiology may vary by location. OBJECTIVES To systematically review the incidence and prevalence of long-term neurological conditions in the UK since 1988. SEARCH(More)
A fully Bayesian analysis of directed graphs, with particular emphasis on applications in social networks, is explored. The model is capable of incorporating the effects of covariates, within and between block ties and multiple responses. Inference is straightforward by using software that is based on Markov chain Monte Carlo methods. Examples are provided(More)
BACKGROUND While ethnic disparities in health and health care are increasing, evidence on how to enhance quality of care and reduce inequalities remains limited. Despite growth in the scope and application of guidelines on "cultural competence," remarkably little is known about how practising health professionals experience and perceive their work with(More)
BACKGROUND There are now effective drugs to prevent cardiovascular disease and guidelines recommend their use. Patients do not always choose to accept preventive medication at levels of risk reduction recommended in guidelines. The purpose of the study was to identify and explore the attitudes of patients and general practitioners towards preventative(More)
BACKGROUND Recent debate suggests Huntington's disease (HD) may be more prevalent than previously reported. In addition, relatively little is known about current disease management. This study aims to provide epidemiological data and describe the pharmacological management of HD in the United Kingdom. METHODS A primary care research database was accessed(More)
BACKGROUND A pilot project cardiovascular prevention was implemented in Sandwell (West Midlands, UK). This used electronic primary care records to identify untreated patients at high risk of cardiovascular disease then invited these high risk patients for assessment by a nurse in their own general practice. Those found to be eligible for treatment were(More)