Paolo Misericordia

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To establish the antihyperglycemic mechanisms of metformin in non-insulin-dependent diabetes mellitus (NIDDM) independently of the long-term, aspecific effects of removal of glucotoxicity, 21 NIDDM subjects (14 obese, 7 nonobese) were studied on two separate occasions, with an isoglycemic (plasma glucose approximately 9 mM) hyperinsulinemic (two-step(More)
Inasmuch as previous studies have obtained conflicting results on the contribution of obesity to insulin resistance in noninsulin-dependent diabetes mellitus (NIDDM), we studied 10 nonobese and 10 obese NIDDM patients with the isoglycemic-(approximately 10 mmol/L)-hyperinsulinemic clamp (two insulin infusions of 4 and 40 mU/m-2 min-1), combined with(More)
OBJECTIVE To assess General Pratictioner's (GPs) knowledge and attitudes about HPV infection and prevention. DESIGN AND PARTICIPANTS A semi-structured survey was conducted from November to December 2013 among Italian GPs. Descriptive and univariate analyses were carried out. MAIN OUTCOME MEASURES AND RESULTS 938 GPs were included in the study. 15%(More)
To discriminate between true secondary failure (TF) and pseudo-secondary failure (PF) to oral hypoglycaemic agents, we studied 34 non-obese non-insulin-dependent diabetic patients who were being treated with these drugs. Nine were in good control (GC) with oral treatment, while 25 showed apparent SF. During a controlled hospital diet, fasting blood glucose(More)
The aim of the Nu.Sa. project is the definition of national level data standards to collect data coming from General Practitioners' Electronic Health Records and to allow secure data sharing between them. This paper introduces the Nu.Sa. framework and is mainly focused on security issues. A solution for secure data sharing and service interoperability is(More)
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