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A descriptive epidemiological survey was extended to the whole province of Sassari, northern Sardinia between latitudes 40 degrees 30' N and 41 degrees N. Results showed a crude total prevalence rate of 144.4 per 100000 on prevalence day (31 December 1997), and an onset-adjusted prevalence rate of 149.7 per 100000. The total average annual incidence rate(More)
Neisseria meningitidis group B (MenB) is a leading cause of meningitis and sepsis. A new vaccine has been recently licensed. The aim of the present study was to evaluate the epidemiology of MenB disease in pediatric age and define the optimal age for vaccination. All patients aged 0-18 years admitted with a diagnosis of meningitis or sepsis to the 83(More)
OBJECTIVES To update prevalence and incidence rates of MS among Sardinians. MATERIALS AND METHODS The present work is a "spider" kind of population based survey, conducted over the interval 1968-97, on patients with MS (Poser criteria) living in the province of Sassari, Northern Sardinia (454,904 population). RESULTS A crude total prevalence rate of(More)
Several lines of evidence indicate a genetic contribution to multiple sclerosis (MS) both in terms of predisposition to the disease and of immunological mechanisms which are known to play crucial roles in MS pathogenesis. The presence of high- and low-risk areas for MS in neighbouring regions supports the theory that MS predisposition is influenced by a(More)
Linezolid is used off-label to treat multidrug-resistant tuberculosis (MDR-TB) in absence of systematic evidence. We performed a systematic review and meta-analysis on efficacy, safety and tolerability of linezolid-containing regimes based on individual data analysis. 12 studies (11 countries from three continents) reporting complete information on safety,(More)
BACKGROUND Human Papillomavirus (HPV) is the most common sexually transmitted infection. The main risk factors correlated with HPV infection are: early sexual debut, the number of partners, frequency and type of sexual contact and partner's sexual histories.We surveyed sexual habits among young people in order to provide information that might orient(More)
BACKGROUND Human papillomavirus (HPV) has been associated with several disorders of the genital tract, skin and oropharynx. The aims of our study were to evaluate the prevalence of HPV infection in women between 15 and 54 years of age in North Sardinia, Italy, to identify the prevalence of High Risk - Human papillomaviruses (HR-HPV) genotypes and to(More)
BACKGROUND The present study assessed microbial contamination in Italian dental surgeries. METHODS An evaluation of water, air and surface microbial contamination in 102 dental units was carried out in eight Italian cities. RESULTS The findings showed water microbial contamination in all the dental surgeries; the proportion of water samples with(More)
Breast cancer is one of the most important neoplasia among women. To reduce its incidence and mortality impact it would be desirable to early identify risk factors associated with its development. It was recently suggested that biological agents could be the etiological cause, particularly Human Papilloma Virus (HPV). No specific relationship with different(More)
4 Bastin AJ, Starling L, Ahmed R, et al. High prevalence of undiagnosed and severe chronic obstructive pulmonary disease at first hospital admission with acute exacerbation. Health status assessment in routine clinical practice: the chronic obstructive pulmonary disease assessment test score in outpatients. Total mortality after changes in leisure time(More)