Paolo Balducci

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Type I diabetes is an autoimmune and a polygenic disease, in which MHC-class II genes contribute to 48% of the disease. The aim of the present study, is to provide a guideline to understanding the molecular association of these genes, through the immunogenetic analysis of 3 Latin american mestizo populations. We included 606 individuals, 349 patients with(More)
We evaluated 91 newly diagnosed IDDM children mean age 7.8 ± 4.5 yrs; 56.7% had had an upper respiratory infection prior to diagnosis and 12.7% had had either mumps or varicella. Peak incidence of disease was found in February and March and August to October. Eighty seven percent had HLA-DR3 and/or DR4 vs 37% of the Venezuelan general population; 81.6% were(More)
Vitiligo is a common depigmenting skin disease, associated with certain autoimmune endocrinopathies, and autoantibodies to several antigens can be found in melanoma cells. We set out to identify the antigens. We examined 26 patients with vitiligo and associated endocrine disease. Of these, 18 patients (77%) and 8 immediate family members had autoantibodies(More)
BACKGROUND Data on chronic pancreatitis prevalence are scanty and usually limited to hospital-based studies. AIM Investigating chronic pancreatitis prevalence in primary care. METHODS Participating primary care physicians reported the prevalence of chronic pancreatitis among their registered patients, environmental factors and disease characteristics.(More)
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