Paola Fazi

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The paper illustrates the system WITH (Write on Internet clinical Trials in Haematology) which supports the writing of a clinical trial (CT) document. The requirements of this system have been defined analysing the writing process of a CT and then modelling the content of its sections together with their logical and temporal relationships. The system WITH(More)
In the paper some results of the modelling of the clinical trial (CT) process are presented. CT research is a complex process which includes the protocol editing, its use and implementation in the CT experimentation, and the evaluation of the results. To improve the medical research, it is necessary to consider the CT research process as a whole. We(More)
LAL0201-B protocol patients without additional chemotherapy: results of the GIMEMA in elderly Philadelphia chromosome-positive acute lymphoblastic leukemia Imatinib plus steroids induces complete remissions and prolonged survival (3667 articles) Clinical Trials and Observations (1615 articles) Brief Reports Articles on similar topics can be found in the(More)
BACKGROUND Recent advances in genetic characterization of acute myeloid leukemia indicate that combined cytogenetic and molecular analyses provide better definition of prognostic groups. The aim of this study was to verify this prospectively in a large group of patients. DESIGN AND METHODS Genetic characterization was prospectively carried out in 397(More)
BACKGROUND The aim of the study was to evaluate the outcome of acute myeloid leukaemia (AML) in patients with a previous malignancy (sAML) treated with chemo- and/or radiotherapy, enrolled in conventional trials. PATIENTS AND METHODS In a multicentre setting, a prospective non-concurrent analysis was performed on 2513 new AML patients, aged 12-78 years,(More)
A case of reversible encephalopathy during treatment with Amphotericin-B (AMB) is described. The comparison of the clinical course of AMB encephalopathy with total dose of AMB, cranial radiotherapy and MRI data available in previously reported cases, shows that this complication is characterized by a progressive, dose-dependent course, possibly influenced(More)
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