Pao-Liang Chen

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Our objectives were to fabricate three-dimensional collagen/chondroitin sulfate beads using mild conditions and no chemical reagents, and subsequently to investigate the influence of the nanotopography of these beads on primary osteoblast and MG63 cell responses, including cell morphology, proliferation rate, and gene expression. The major principle used to(More)
The aim of this work was to develop a novel method for preparing a three-dimensional bone-like matrix comprising nanohydroxyapatite crystals and fibrous collagen and to apply it for bone tissue engineering. Hydroxyapatite and collagen are the major components of natural hard bone. Therefore, they have been used extensively in orthopedic surgery as(More)
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