Pantelis Vlachos

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Mammalian central nervous system (CNS) development is a highly organized process involving the precise and coordinated timing of cell-cycle exit, differentiation, survival, and migration. These events require proper expression of pro-neuronal genes but also repression of alternative cell fates and restriction of cell-type-specific gene expression. Here, we(More)
p57 (Kip2, cyclin-dependent kinase inhibitor 1C), often found downregulated in cancer, is reported to hold tumor suppressor properties. Originally described as a cyclin-dependent kinase (cdk) inhibitor, p57(KIP2) has since been shown to influence other cellular processes, beyond cell cycle regulation, including cell death and cell migration. Inhibition of(More)
AIMS The aim of the study was to compare the pharmacokinetics (PK), safety and tolerability of the proposed adalimumab biosimilar MSB11022 (Merck) with Humira(®) (AbbVie), sourced from both the US (US reference product [US-RP]) and Europe (European reference medicinal product [EU-RMP]). METHODS In this phase 1 double-blind, parallel group trial(More)
Awards Two National Academy Awards and different Stipends, fellowships and prizes Ad hoc reviewer (1973) «Hydroxyproline excretion in pituitary dwarfs treated with therapeutic doses of human growth hormone». Hormone Res. 4: 311-320 2. «Effects of imipramine on serum LDH and alkaline phospatase activity and elecrolyete concentrations in mental patients» IRCS(More)
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