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Jet lag has potentially serious deleterious effects on performance in athletes following transmeridian travel, where time zones are crossed eastwards or westwards; as such, travel causes specific effects related to desynchronization of the athlete's internal body clock or circadian clock. Athletes are particularly sensitive to the effects of jet lag, as(More)
The surface is of critical importance in determining the in vivo performance and acceptance of an implant, with respect to both tissue and blood. Material surface properties have been studied intensively, but only in recent years have quantitative, mechanistic links been made to biomolecular and cellular interactions driven by the surface. This review(More)
Rapid biochemical testing can expedite therapy i n key patient categories, particularly intensive care. Dry reagent chemistries have gone some way t o s a t i s f y i n g some of t h e s e requirements. However, chemical a n d b i o s e n s o r s o f f e r t h e p r o s p e c t s f o r more r o b u s t a n d operationally simpler near-patient analysers(More)
Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide, but credible estimates from the World Health Organization and the International Agency for Research on Cancer (IARC) suggest that the fraction of cancers attributable to toxic environmental exposures is between 7% and 19%. To explore the hypothesis that low-dose(More)
Silver-particle-incorporated polyurethane films were evaluated for antimicrobial activity towards two different bacteria: Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). Distributed silver particles sourced from silver nitrate, silver lactate and preformed silver nanoparticles were mixed with polyurethane (PU) and variously characterized(More)
This work presents the design, fabrication, and characterization of a robust 3D printed microfluidic analysis system that integrates with FDA-approved clinical microdialysis probes for continuous monitoring of human tissue metabolite levels. The microfluidic device incorporates removable needle type integrated biosensors for glucose and lactate, which are(More)
To enable continuous monitoring of electrochemical sensors outside the laboratories, there is a significant demand on electrochemical measurement systems to be miniaturized. The paper presents a low-cost, portable miniature device for electrochemical measurements. The device consists of a 35mm × 20mm × 25mm wireless tag, which enables(More)
Lactate is one of the most important biomarkers of tissue oxygenation and thus of paramount importance for sports and health care applications. Lactate levels provide information on anaerobic threshold which is very important for tailoring training programs in endurance sports. In this contribution we present an implantable amperometric lactate sensor for(More)
Analytical expressions for solute diffusion through a membrane barrier for different initial and boundary conditions are available in the literature. The three commonest initial and boundary conditions are for a membrane without solute respectively immersed in a solution of constant concentration, immersed in such a solution for one side but with the other(More)