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The genetics of human phenotype variation and especially, the genetic basis of human complex diseases could be understood by knowing the functions of Single Nucleotide Polymorphisms (SNPs). The main goal of this work is to predict the deleterious non-synonymous SNPs (nsSNPs), so that the number of SNPs screened for association with disease can be reduced to(More)
Shape descriptors are more powerful to discern objects present in the images. The present work is focused on simple contour based shape descriptor using centroid distance function and it works on closed contour objects. Object area normalization is performed to obtain `N' normalized contour points. The centroid distance feature extraction is performed on(More)
Regioselective facile one-pot synthesis of 16 different sugar-based quinoline, naphthyridine, and xanthone derivatives is reported. The compounds are characterized by NMR spectroscopy and elemental analysis. The beta-Anomeric form of the sugar moiety was identified from (1)H NMR studies. Antimicrobial studies of these sugar-heterocyclic derivatives, 3a, 3b,(More)
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