Panagiotis Asimakopoulos

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BACKGROUND Abnormal vascular responsiveness to vasoconstrictors may play an important role in peripheral vascular resistance in hyperthyroidism. The aim of the present study was to evaluate whether the vascular response to potassium chloride and phenylephrine is abnormal in a rat model of thyroxine-induced cardiac hypertrophy. METHODS Left ventricular(More)
BACKGROUND The issue of whether to adopt a "wait and watch" strategy or to initiate drug therapy soon after diagnosis in Parkinson's disease (PD) has been the subject of some debate. A recent observational study supported early treatment by demonstrating deterioration in self-reported health status in those left untreated, but not those who received(More)
OBJECTIVES Low back pain is related to functional status and possible resulting disability. The Quebec Back Pain Disability Scale (QBPDS) has been used widely to evaluate functional disability in patients with low back pain. The purpose of this study was to assess: (a) the face and content validity, (b) the factor structure, (c) the concurrent validity, (d)(More)
Thyroid cancer metastasises to the central and lateral compartments of the neck frequently and early. The impact of nodal metastases on outcome is affected by the histological subtype of the primary tumour and the patient's age, as well as the size, number and location of those metastases. The impact of extranodal extension has recently been highlighted as(More)
BACKGROUND There is no consensus as to whether all routine bilateral polypectomy specimens should be sent for formal histopathological diagnosis to exclude underlying neoplastic pathology. This study assessed the necessity for histopathological investigation as routine practice in cases of bilateral and unilateral nasal lesions by estimating the incidence(More)
3 4 The abstracts in this Programme have been reproduced directly from word processed files provided by authors; the British Geriatrics Society has no responsibility for the scientific content. ___________________________________________ Background Vitamin D deficiency in older people is associated with poor health outcomes but remediable by public health(More)
The majority of patients who present with well differentiated thyroid cancer will require surgery, but decisions on the appropriate primary procedure will depend on information relating to patient, tumour and surgical factors. As the incidence of thyroid cancer continues to rise, it is critical that clinicians involved in the management of these cases(More)