Pamela M Jones

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In a double blind, randomised trial, the effects of 1 g aspirin and 1 g paracetamol were compared on bleeding time and platelet aggregation in 40 volunteers (20 females). Also investigated was the relationship between plasma aspirin esterase activity and both bleeding time and platelet aggregation after aspirin. Following 1 g aspirin there was a significant(More)
In 1977, a program of early, wide-field radiation therapy (RT) to the central nervous system and repeated lumbar intrathecal (IT) medications along with systemic chemotherapy was begun by the Intergroup Rhabdomyosarcoma Study (IRS) for patients younger than 21 years of age with cranial parameningeal sarcoma and a high risk of meningeal extension. From 1977(More)
The medical records of 116 consecutive cases of congenital diaphragmatic hernia (CHD) among 368,772 live births at the three maternity hospitals in Dublin were examined and the incidence of associated malformations and their impact on survival analysed. The patients were divided into two groups: group I included 64 (55%) patients who died during(More)
OBJECTIVES We studied the feasibility of implementing a community-based participatory process (CBPP) that addressed cancer education, prevention, and screening in 2 ethnic minority populations by evaluating the improvement in rates of cancer screening compared with historical benchmarks. METHODS From 2003 to 2009, 2281 community members participated in(More)
Between 1954 and 1985, 15 cases of malignant sacrococcygeal teratoma were treated in our institution. Median age at presentation was 20 months (range 9–46 months); there were 14 females and 1 male. Six cases presenting prior to 1970 were treated without chemotherapy with a median survival of 2 months (range 1–7 months). Five patients treated from 1971 to(More)
BACKGROUND Subcutaneous emphysema may complicate a pneumothorax, but may also occur as a consequence of its treatment by chest tube drainage. The aim of this study was to evaluate the factors involved in the association between subcutaneous emphysema and chest tube drainage, and the clinical outcomes in these cases. METHODOLOGY One hundred and sixty-seven(More)
BACKGROUND Data on patients who received breast-conserving therapy (BCT) for early stage breast cancer were examined to detect differences in disease presentation, management techniques, long-term treatment outcomes, and toxicities based on race. METHODS Six hundred ninety-nine women with breast cancer (39 African-American [AA] women and 660 Caucasian [C](More)
AIM This study aimed to assess the effect of atropine premedication prior to flexible bronchoscopy. The rationale for using atropine is that it will dry secretions and allow a better view of the bronchial tree. There is also the theoretical benefit of protection against vasovagal episodes and bronchospasm. METHODS Twenty patients were randomised in a(More)
OBJECTIVES We analyzed differences in disease presentation, outcomes, and toxicities between African American (AA) and White (W) men treated with definitive radiation therapy for their prostate cancer. METHODS Three thousand one hundred eighty cases of prostate cancer treated with various radiation modalities at a single institution were reviewed. The(More)
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