Pamela L. C. Small

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Ecology and Transmission of Buruli Ulcer Disease: A Systematic Review

Richard W. Merritt, Edward D. Walker, +4 authors Daniel Adjei Boakye
PLoS neglected tropical diseases
2010

Buruli ulcer is a neglected emerging disease that has recently been reported in some countries as the second most frequent mycobacterial disease in humans after tuberculosis. Cases have been reported… (More)

Distribution of Mycobacterium ulcerans in Buruli Ulcer Endemic and Non-Endemic Aquatic Sites in Ghana

Heather R Williamson, M Eric Benbow, +8 authors Pamela L. C. Small
PLoS neglected tropical diseases
2008

Mycobacterium ulcerans, the causative agent of Buruli ulcer, is an emerging environmental bacterium in Australia and West Africa. The primary risk factor associated with Buruli ulcer is proximity to… (More)

Global Morbidity and Mortality of Leptospirosis: A Systematic Review

Federico Costa, Jose E Hagan, +7 authors Pamela L. C. Small
PLoS neglected tropical diseases
2015

BACKGROUND Leptospirosis, a spirochaetal zoonosis, occurs in diverse epidemiological settings and affects vulnerable populations, such as rural subsistence farmers and urban slum dwellers. Although… (More)

First Cultivation and Characterization of Mycobacterium ulcerans from the Environment

Françoise Portaels, Wayne M. Meyers, +14 authors Jorge M Pedrosa
PLoS neglected tropical diseases
2008

BACKGROUND Mycobacterium ulcerans disease, or Buruli ulcer (BU), is an indolent, necrotizing infection of skin, subcutaneous tissue and, occasionally, bones. It is the third most common human… (More)

Detection of Mycobacterium ulcerans in the Environment Predicts Prevalence of Buruli Ulcer in Benin

Heather R Williamson, M Eric Benbow, +5 authors Pamela L. C. Small
PLoS neglected tropical diseases
2012

BACKGROUND Mycobacterium ulcerans is the causative agent of Buruli ulcer (BU). In West Africa there is an association between BU and residence in low-lying rural villages where aquatic sources are… (More)

A Mycobacterium ulcerans toxin, mycolactone, induces apoptosis in primary human keratinocytes and in HaCaT cells.

Chiarella Bozzo, Rossana Tiberio, +5 authors Giorgio Leigheb
Microbes and infection
2010

The pathogenicity of Mycobacterium ulcerans (Buruli ulcer) depends on cytotoxic effect of its exotoxin mycolactone. Since epidermis represents a barrier against infectious agents and balanced… (More)

The inhibitory action of Mycobacterium ulcerans soluble factor on monocyte/T cell cytokine production and NF-kappa B function.

Ali Akbar Pahlevan, Daniel J Wright, Charles William . Andrews, Kathleen M. George, Pamela L. C. Small, Brian M. J. Foxwell
Journal of immunology
1999

Buruli ulcer is a chronic and progressive necrotizing ulcer for which there is no medical treatment. Historically, a soluble toxin (factor) derived from the causative Mycobacterium ulcerans was found… (More)

A Landscape-based Model for Predicting Mycobacterium ulcerans Infection (Buruli Ulcer Disease) Presence in Benin, West Africa

Tyler Wagner, M Eric Benbow, +4 authors Pamela L. C. Small
EcoHealth
2007

Mycobacterium ulcerans infection (Buruli ulcer [BU] disease) is an emerging tropical disease that causes severe morbidity in many communities, especially those in close proximity to aquatic… (More)

Mycetoma Medical Therapy

Oliverio Welsh, Hail Mater Al-Abdely, Mario César Salinas-Carmona, Ahmed Hassan Fahal, Pamela L. C. Small
PLoS neglected tropical diseases
2014

Medical treatment of mycetoma depends on its fungal or bacterial etiology. Clinically, these entities share similar features that can confuse diagnosis, causing a lack of therapeutic response due to… (More)

Global Burden of Leptospirosis: Estimated in Terms of Disability Adjusted Life Years

Paul Robert Torgerson, Jose E Hagan, +8 authors Pamela L. C. Small
PLoS neglected tropical diseases
2015

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