Pamela F. Olson

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Laminins are heterotrimeric molecules composed of an a , a b , and a g chain; they have broad functional roles in development and in stabilizing epithelial structures. Here, we identified a novel laminin, composed of known a and b chains but containing a novel g chain, g 3. We have cloned gene encoding this chain, LAMC3, which maps to chromosome 9 at(More)
The netrins are a family of laminin-related molecules. Here, we characterize a new member of the family, b -netrin. b -Netrin is homologous to the NH 2 terminus of laminin chain short arms; it contains a laminin-like domain VI and 3.5 laminin EGF repeats and a netrin C domain. Unlike other netrins, this new netrin is more related to the laminin b chains,(More)
Laminins are heterotrimeric molecules composed of an a , a b , and a g chain; they have broad functional roles in development and in stabilizing epithelial structures. Here, we identified a novel laminin, composed of known a and b chains but containing a novel g chain, g 3. We have cloned gene encoding this chain, LAMC3, which maps to chromosome 9 at(More)
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