Paloma Fernández-Rodríguez

  • Citations Per Year
Learn More
Background Hydrocephalus is a disorder characterized by brain ventricular dilation and excess of cerebrospinal fluid (CSF), in many cases its etiopathic origin is acquired as: post-hemorrhage, meningitis and tumours. But, there is no attributable cause in 45% of hydrocephalus cases and foetal hydrocephalus due to aqueductal stenosis is one of the two main(More)
The objective of this study was to analyze the proteins in the cerebrospinal fluid of spontaneously hypertensive rats and to study their possible role in the relationship between hydrocephalus, arterial hypertension and variations in the subfornical organ. Brains and cerebrospinal fluid from control Wistar-Kyoto rats and spontaneously hypertensive rats(More)
Reissner's fibre (RF) is formed by the polymerization of the glycoprotein secreted by the subcommissural organ (SCO). The SCO also secretes soluble glycoprotein into the cerebrospinal fluid (CSF); variations in RF and SCO have been reported in hydrocephalus. On the other hand, hydrocephalus and other brain alterations have been described in p73 mutant mice.(More)
Background Arterial hypertension produces ventricular dilation, CSF protein composition variations as well as alterations in the circumventricular organ and choroid plexus (CP). Cerebrospinal fluid (CSF) has an important relationship with the blood and the brain, and encephalic pathology could alter the connections between the blood, brain and CSF, and(More)
The aim of this work was to analyze the proteins in the cerebrospinal fluid (CSF) of spontaneously hypertensive rats, to study their possible role in the relationship between hydrocephalus, arterial hypertension and alterations in the subcommissural organ. Brains from control Wistar-Kyoto rats (WKY) and spontaneously hypertensive rats (SHR) sacrificed with(More)
Background Reissner's fibre (RF) is formed by the polymerisation of the glycoprotein secreted by the subcommissural organ (SCO). The SCO also secretes soluble glycoprotein into the cerebrospinal fluid (CSF), variations in the RF and SCO have been reported in hydrocephalus. The protein p73 belongs to the tumor suppressor factor family, which also includes(More)
ss Open Acce Poster presentation p73 and transthyretin expression in circumventricular organs in kaolin-induced and spontaneously hydrocephalic rats Emilia M Carmona-Calero*1,2, Juan M Gonzalez-Toledo1, Ibrahim GonzálezMarrero2, Paloma Fernández-Rodríguez2, Hector de Paz-Carmona1, Leandro Castañeyra-Ruiz2, Maria A Marichal2, Agustín Castañeyra-Ruiz2, Isabel(More)
Background It has been reported that the blood pressure high (BPH) mouse shows an increase in blood pressure and alterations in the brain catecholaminergic system as well as normal ventricular size. However, spontaneously hypertensive rats (SHR) show ventricular dilation, changes in CSF proteins and variations in the brain angiotensin-vasopressin system.(More)
Open Access Poster presentation without discussion Expression of certain cerebrospinal fluid proteins in hydrocephalus and aging. A study on WKY rats Ibrahim Gonzalez-Marrero1,2, Paloma Fernández-Rodríguez1, Herminia Perez-Gonzalez2, Leandro Castañeyra-Ruiz*1, Agustin CastañeyraRuiz1, Carlos Ormazabal-Ramos2, Emilia Ma Carmona-Calero1,2, Luz M Fernadez2, M(More)