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Glaucoma is one of the leading cause of blindness. The manual examination of optic cup and disc is a standard procedure used for detecting glaucoma. This paper presents a fully automatic regression based method which accurately segments optic cup and disc in retinal colour fundus image. First, we roughly segment optic disc using circular hough transform.(More)
Retinal image quality assessment (IQA) algorithms use different hand crafted features for training classifiers without considering the working of the human visual system (HVS) which plays an important role in IQA. We propose a convolutional neural network (CNN) based approach that determines image quality using the underlying principles behind the working(More)
Retinal fundus images are mainly used by ophthalmologists to diagnose and monitor the development of retinal and systemic diseases. A number of computer-aided diagnosis (CAD) systems have been developed aimed at automation of mass screening and diagnosis of retinal diseases. Eye type (left or right eye) of a given retinal image is an important meta data(More)
White matter lesions (WMLs) are small groups of dead cells that clump together in the white matter of brain. In this paper, we propose a reliable method to automatically segment WMLs. Our method uses a novel filter to enhance the intensity of WMLs. Then a feature set containing enhanced intensity, anatomical and spatial information is used to train a random(More)
In this paper, a fully automated segmentation method is proposed to identify Multiple Sclerosis (MS) related white matter lesions from brain magnetic resonance imaging (MRI) data. The main contribution of this paper is to obtain a new texture feature set for MS Lesion segmentation that is a combination of local and global neighbourhood information. The(More)
Multi-atlas segmentation first registers each atlas image to the target image and transfers the label of atlas image to the coordinate system of the target image. The transferred labels are then combined, using a label fusion algorithm. In this paper, we propose a novel label fusion method which aggregates discriminative learning and generative modeling for(More)
Recent studies show that, cerebral White Matter Lesion (WML) is related to cerebrovascular diseases, cardiovascular diseases, dementia and psychiatric disorders. Manual segmentation of WML is not appropriate for long term longitudinal studies because it is time consuming and it shows high intra-and inter-rater variability. In this paper, a fully automated(More)
Retinal arteriovenous (AV) nicking is a precursor for hypertension, stroke and other cardiovascular diseases. In this paper, an effective method is proposed for the analysis of retinal venular widths to automatically classify the severity level of AV nicking. We use combination of intensity and edge information of the vein to compute its widths. The widths(More)
We present a novel method for the quantification of focal arteriolar narrowing (FAN) in human retina, a precursor for hypertension, stroke and other cardiovascular diseases. A reliable and robust arteriolar boundary mapping method is proposed where intensity, gradient and spatial prior knowledge about the arteriolar shape is incorporated into a graph based(More)