Pakeeza Arzoo Shaiq

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BACKGROUND Genetic predisposition to psoriasis, an inflammatory skin disease affecting 0·2-4% of the world population, is well established. Thus far, 41 psoriasis susceptibility loci reach genome-wide significance (P ≤ 5 × 10(-8) ). Identification of genetic susceptibility loci in diverse populations will help understand the underlying biology of psoriasis(More)
Exome sequencing has become more and more affordable and the technique has emerged as an important diagnostic tool for monogenic disorders at early stages of investigations, in particular when clinical information is limited or unspecific as well as in cases of genetic heterogeneity. We identified a consanguineous Pakistani family segregating an autosomal(More)
1Department of Dermatology, University of Michigan, Ann Arbor, MI, USA 2Department of Biochemistry, PMASAA University, Rawalpindi, Pakistan 3Institute of Dermatology, Bangkok, Thailand 4COMSATS Institute of Information Technology, Islamabad, Pakistan 5Al-Nafees Medical College and Hospital, Isra University, Islamabad, Pakistan 6Department of Biostatistics,(More)
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