Padmavathi Sundaram

Darren B Orbach3
Ellen J Bubrick2
3Darren B Orbach
2Ellen J Bubrick
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Neuronal currents produce local electromagnetic fields that can potentially modulate the phase of the magnetic resonance signal and thus provide a contrast mechanism tightly linked to neuronal activity. Previous work has demonstrated the feasibility of direct MRI of neuronal activity in phantoms and cell culture, but in vivo efforts have yielded(More)
The ability to detect neuronal currents with high spatiotemporal resolution using magnetic resonance imaging (MRI) is important for studying human brain function in both health and disease. While significant progress has been made, we still lack evidence showing that it is possible to measure an MR signal time-locked to neuronal currents with a temporal(More)
PURPOSE Reliably detecting MRI signals in the brain that are more tightly coupled to neural activity than blood-oxygen-level-dependent fMRI signals could not only prove valuable for basic scientific research but could also enhance clinical applications such as epilepsy presurgical mapping. This endeavor will likely benefit from an improved understanding of(More)
We recently developed a functional neuroimaging technique called encephalographic magnetic resonance imaging (eMRI). Our method acquires rapid single-shot gradient-echo echo-planar MRI (repetition time=47 ms); it attempts to measure an MR signal more directly linked to neuronal electromagnetic activity than existing methods. To increase the likelihood of(More)
Computed Tomographic Colonography (CTC) produces 2-d and 3-d images of the colon using computed tomography (CT). The main goal of CTC is to detect small lumps on the colon surface called polyps, which are known to be precursors to colon cancer. Radiologists are therefore interested in exploring the inner surface of the colon to detect polyps. Polyps may be(More)
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