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The laboratory mouse shares the majority of its protein-coding genes with humans, making it the premier model organism in biomedical research, yet the two mammals differ in significant ways. To gain greater insights into both shared and species-specific transcriptional and cellular regulatory programs in the mouse, the Mouse ENCODE Consortium has mapped(More)
The trend towards increasing the number of processor cores and cache capacity in future Chip-Multiprocessors (CMPs), will require scalable packet-switched interconnection networks adapted to the restrictions imposed by the CMP environment. This paper presents an innovative router design, which successfully addresses CMP cost/performance constraints. The(More)
This paper presents a simple but effective method to reduce on-chip access latency and improve core isolation in CMP Non-Uniform Cache Architectures (NUCA). The paper introduces a feasible way to allocate cache blocks according to the access pattern. Each L2 bank is dynamically partitioned at set level in private and shared content. Simply by adjusting the(More)
Genomic studies of endangered species provide insights into their evolution and demographic history, reveal patterns of genomic erosion that might limit their viability, and offer tools for their effective conservation. The Iberian lynx (Lynx pardinus) is the most endangered felid and a unique example of a species on the brink of extinction. We generate the(More)
BACKGROUND Several studies have examined the effect of irritable bowel syndrome (IBS) on health outcomes in Western Europe, but less research has focused on the constipation subtype (IBS-C). The current study addresses this gap by comparing patients with IBS-C and matched controls for health status, work productivity, and resource utilization. METHODS(More)
The real time computer for controlling and regulating the FNAL Main Ring power supplies has been upgraded with a new learning control system. The learning time of the system has been reduced by an order of magnitude, mostly through the implementation of a 95 tap FIR filter in the learning algorithm. The magnet system consists of three buses, which must(More)
c, damping ring and extraction line, as of year 2008 PM stations. Tabl a in parameters bstract A beam position monitor (BPM) upgrade at the KEK Accelerator Test Facility (ATF) damping ring has been accomplished in its first stage, carried out by a KEK/FNAL/SLAC collaboration under the umbrella of the global ILC R&D effort. The upgrade consists of a high(More)