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Chronic maternal stress during pregnancy has been associated with behavioral alterations that persist into adulthood. Moreover, adoption procedures performed immediately after birth can reverse these alterations. In this study, we examined the effects of prenatal restraint stress and adoption at birth (cross-fostering) on the behavioral response to an(More)
RATIONALE AND OBJECTIVES Duration of weaning from mechanical ventilation may be reduced by the use of a systematic approach. We assessed whether a closed-loop knowledge-based algorithm introduced in a ventilator to act as a computer-driven weaning protocol can improve patient outcomes as compared with usual care. METHODS AND MEASUREMENTS We conducted a(More)
BACKGROUND Acquired diffuse paresis in an intensive care unit (ICU) can result from critical illness myopathy or polyneuropathy. Clinical examination and conventional neurophysiological techniques may not distinguish between these entities. OBJECTIVE To assess the value of direct muscle stimulation (DMS) to differentiate myopathic from neuropathic process(More)
INTRODUCTION The aim of this study was to determine the relationship between hormonal status and mortality in patients with protracted critical illness. METHODS We conducted a prospective observational study in four medical and surgical intensive care units (ICUs). ICU patients who regained consciousness after 7 days of mechanical ventilation were(More)
read with interest the study by Routsi and colleagues showing that electrical muscle stimulation (EMS) reduced the frequency of critical illness polyneuropathy in intensive care unit (ICU) patients [1]. Th e authors stated that an intention-to-treat analysis was used. One hundred and forty patients were randomized to electrical stimulation or to usual care.(More)
This paper reports a longitudinal study of 19 patients diagnosed as having pseudodementia more than a decade earlier. In only one patient was the earlier diagnosis changed to definite dementia and, in this patient, there were strong indicators that such a diagnosis should have been made initially. In a second patient, dementia could not be excluded. The(More)
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