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The present study investigated the sensitivity and specificity of the Hopkins Verbal Learning Test (HVLT) for demented patients (n = 82, using NINCDS criteria) and 114 healthy controls--equivalent in age, years of education and gender-ratio--from the Oxford Project to Investigate Memory and Ageing. The HVLT 'Total Recall' score had 87% sensitivity and 98%(More)
Schematic eyes for four Macaca fascicularis monkeys were constructed from measurements of the positions and curvatures of the anterior and posterior surfaces of the cornea and lens. All of these measurements were obtained from Scheimpflug photography through the use of a ray-tracing analysis. Some of these measurements were also checked (and confirmed) by(More)
BACKGROUND Several factors are thought to influence resource use and costs in treating schizophrenia. AIMS To assess the relative impact of non-adherence and other factors associated with resource use and costs incurred by people with schizophrenia. METHOD Secondary analyses were made of data from a 1994 national survey of psychiatric morbidity among(More)
The Hopkins Verbal Learning Test (HVLT) and the Mini-Mental State Examination (MMSE) were administered to 323 non-demented elderly and 70 individuals who meet DSM-IV criteria for dementia in order to compare the validity of these two measures for detecting mild dementia and for the two most common dementia subtypes, Alzheimer's disease (AD) and vascular(More)
This study evaluated the use of walking speed as an indicator of function and health status in acutely ill, hospitalized, older male veterans. Hospital inpatients in a Department of Veterans Affairs (VA) study of Geriatric Evaluation and Management (GEM) (n = 1,388, age 74.2 +/- 5.7, 98% male) were followed for 1 year. The results indicate that each 0.10(More)
Our aim was to compare the predictive accuracy of 4 different medial temporal lobe measurements for Alzheimer's disease (AD) in subjects with mild cognitive impairment (MCI). Manual hippocampal measurement, automated atlas-based hippocampal measurement, a visual rating scale (MTA-score), and lateral ventricle measurement were compared. Predictive accuracy(More)
BACKGROUND Early screenings involving biomarkers and use of potential disease-modifying therapies (DMTs) may have significant humanistic implications for treatment strategies in Alzheimer's disease. METHODS Markov models simulated transitions of patient cohorts beginning in predementia, a hypothetical early stage of Alzheimer's disease marked by objective(More)
BACKGROUND Despite heavy recent emphasis on blood pressure (BP) control, many patients fail to meet widely accepted goals. While access and adherence to therapy certainly play a role, another potential explanation is poor quality of essential care processes (QC). Yet little is known about the relationship between QC and BP control. METHODS We assessed QC(More)
have commented about the model calibration, neural network design, and logistic regression models in our study, which used neural networks to predict perioperative cardiac risk.2 2 They maintain that the likelihood-ratio calculations were invalid unless the neural network scores had normal distributions for patients with and without cardiac events.'(More)
We identified articles on the evaluation and management of headache by conducting a MEDLINE search of English language articles between 1990 and 1995 (keywords headache, diagnosis, treatment) and by reviewing two textbooks on primary care (Pruitt, in Goroll et al., 1995; Bleeker and Meyd, in Barker et al., 1991) and one for children and adolescents (Prensky(More)