Pablo Fernandez

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This paper performs an unprecedented comparative study of Metaheuristic optimization frameworks. As criteria for comparison a set of 271 features grouped in 30 characteristics and 6 areas has been selected. These features include the different metaheuristic techniques covered, mechanisms for solution encoding, constraint handling, neighborhood(More)
BACKGROUND Pregnancy-associated malaria (PAM) is a serious consequence of Plasmodium falciparum-infected erythrocytes sequestration in the placenta through the adhesion to the placental receptor chondroitin sulfate A (CSA). Although women become resistant to PAM as they acquire transcending inhibitory immunity against CSA-binding parasites, hundreds of(More)
BACKGROUND Pregnancy-associated malaria (PAM) is a serious consequence of the adhesion to the placental receptor chondroitin sulfate A (CSA) of Plasmodium falciparum-infected erythrocytes (PE) expressing the large cysteine-rich multi-domain protein var2CSA. Women become resistant to PAM, and develop strain-transcending immunity against CSA-binding(More)
In service oriented scenarios, applications are created by composing atomic services and exposing the resulting added value logic as a service. When several alternative service providers are available for composition , quality of service (QoS) properties such as execution time, cost, or availability are taken into account to make the choice, leading to the(More)
Traditionally, Service Level Agreements have been decomposed in two sets of properties: functionals (what) and non-functionals (how). However, in our opinion, there has been a third key element that has had a minor attention from academy: temporal awareness (when). We believe temporality is a main concern that should be addressed in realistic scenarios. In(More)
Glyphosate is a broad-spectrum systemic herbicide used to kill weeds, especially annual broadleaf weeds and grasses known to compete with commercial crops grown around the globe. However, weeds evolve and develop resistance to glyphosate. Until recently, no case of glyphosate resistance had been detected in France. Glyphosate resistance was indeed recently(More)