Pablo Fernandez

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This paper performs an unprecedented comparative study of Metaheuristic optimization frameworks. As criteria for comparison a set of 271 features grouped in 30 characteristics and 6 areas has been selected. These features include the different metaheuristic techniques covered, mechanisms for solution encoding, constraint handling, neighborhood(More)
BACKGROUND Pregnancy-associated malaria (PAM) is a serious consequence of Plasmodium falciparum-infected erythrocytes sequestration in the placenta through the adhesion to the placental receptor chondroitin sulfate A (CSA). Although women become resistant to PAM as they acquire transcending inhibitory immunity against CSA-binding parasites, hundreds of(More)
BACKGROUND Pregnancy-associated malaria (PAM) is a serious consequence of the adhesion to the placental receptor chondroitin sulfate A (CSA) of Plasmodium falciparum-infected erythrocytes (PE) expressing the large cysteine-rich multi-domain protein var2CSA. Women become resistant to PAM, and develop strain-transcending immunity against CSA-binding(More)
Traditionally, Service Level Agreements have been decomposed in two sets of properties: functionals (what) and non-functionals (how). However, in our opinion, there has been a third key element that has had a minor attention from academy: temporal awareness (when). We believe temporality is a main concern that should be addressed in realistic scenarios. In(More)
In service oriented scenarios, applications are created by composing atomic services and exposing the resulting added value logic as a service. When several alternative service providers are available for composition , quality of service (QoS) properties such as execution time, cost, or availability are taken into account to make the choice, leading to the(More)