Pablo Alberto Chiaradia

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PURPOSE To evaluate the efficacy of corneal cross-linking (CXL; riboflavin/ultraviolet A) as a simple therapy for Acanthamoeba keratitis. METHODS Twenty rabbits were systemically anesthetized and the stroma of their right corneas was inoculated with a suspension of Acanthamoeba. Rabbits were divided into 2 groups: one group was treated with corneal CXL 3(More)
PURPOSE Although corneal power and axial length are known to be inversely correlated, the biological determinants of corneal power are unknown. To elucidate this correlation further, study authors investigated the relationships among corneal power, corneal diameter, anterior chamber diameter, and axial length in a sample of human adults. METHODS The eyes(More)
BACKGROUND Anterior chamber miotic solutions are widely used in ophthalmic surgery to induce pupillary contraction. We investigated whether the acetylcholine, carbachol, or mannitol present in perfusing solutions can affect corneal endothelial function. METHODS Freshly dissected deepithelized rabbit corneas were mounted in a Dikstein-Maurice chamber at 36(More)
BACKGROUND Anterior chamber miotic solutions are widely used during anterior chamber surgery. We examined the effects of solutions containing miotic agents such as carbachol and/or acetylcholine on corneal endothelial pumping activity. METHODS We monitored, in vitro, the transendothelial electrical potential difference of isolated rabbit corneal(More)
BACKGROUND Previous research has found an association between family history and presence of myopia. It is possible that family history also could be related to the final amount of refractive error developed. If that were true, then family history of myopia could have predictive value for the amount of refractive error a child or young adult would develop(More)
PURPOSE To determine the central corneal thickness after administration of the anti-glaucomatous medications latanoprost 0.005% or dorzolamide 2%, as assessed in rabbits which have had total corneal thickness autografts. METHODS A bilateral total corneal thickness autograft was performed in ten rabbits. One rabbit was excluded from the subsequent study in(More)
This case report describes the features of a tuberculous subretinal abscess in a non-HIV patient. It includes the characterization of the lesion with spectral-domain optical coherence tomography (SD-OCT) and fundus autofluorescence examination. SD-OCT and autofluorescence imaging showed external retinal involvement during development of the tuberculous(More)
  • DROGAS ANTIGLAUCOMATOSAS, SOBRE EL ESPESOR, CORNEAL EN CONEJOS, CON AUTOINJERTO, DE CÓRNEA, Pablo Chiaradia
  • 2008
Purpose: To determine the central corneal thickness after administration of the anti-glaucomatous medications latanoprost 0.005% or dorzolamide 2%, as assessed in rabbits which have had total corneal thickness autografts. Methods: A bilateral total corneal thickness autograft was performed in ten rabbits. One rabbit was excluded from the subsequent study in(More)
PURPOSE To examine the effects of n-3 and n-6 polyunsaturated fatty acids (n-3 and n-6 PUFAs) in a murine model of herpetic chorioretinitis. METHODS BALB/c mice were fed on three high fat diets, which contained: Menhaden oil (rich in n-3 PUFAs); Safflower oil (rich in n-6 PUFAs); or Corn oil (rich in saturated fatty acids) as control group, 14 days(More)
BACKGROUND Dry eye disease (DED) is a multifactorial disease of the tears and ocular surface that results in symptoms such as discomfort, visual disturbance, and tear film instability, with potential damage to the ocular surface. The principal pathological mechanisms of DED are hyperosmolarity and inflammation. These mechanisms are deeply interrelated and(More)