Paaladinesh Thavendiranathan

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Bough et al. have recently demonstrated anticonvulsant effects of the 'classic' ketogenic diet (KD) in the pentylenetetrazol infusion model in rats. Proconvulsant effects were seen, however, when the 'classic' diet was tested against maximal electroshock (MES) seizures. These differing results may reflect the fact that the two models involve different kinds(More)
Truncus arteriosus (TA) is a rare congenital condition defined as a single arterial vessel arising from the heart that gives origin to the systemic, pulmonary and coronary circulations. We discuss the unique case of a 28 year-old female patient with unrepaired TA and interruption of the aortic arch who underwent cardiovascular magnetic resonance (CMR).
Following publication of this abstract [1] it was noted by the authors that an incorrect version of Figure 1 had been inadvertently uploaded with the manuscript. The correct version Figure 1 is available below. In addition it was found that the author list was incorrectly ordered, this has been corrected in the author list above. between MRI derived right(More)
Accurate assessment of mitral regurgitation (MR) severity is important for clinical decision making, prognostication, and decisions regarding timing of surgical intervention. The most common method for noninvasive assessment of MR has been with 2-dimensional transthoracic echocardiography, which is often used as a qualitative tool. Several newer noninvasive(More)
BACKGROUND Stress cardiac magnetic resonance (CMR) has typically involved pharmacologic agents. Treadmill CMR has shown utility in single-center studies but has not undergone multicenter evaluation. METHODS AND RESULTS Patients referred for treadmill stress nuclear imaging (SPECT) were prospectively enrolled across 4 centers. After rest (99m)Tc SPECT,(More)
BACKGROUND The aim of this study was to compare left ventricular (LV) remodeling using myocardial strain between patients with severe aortic stenosis (AS) treated with transcatheter aortic valve replacement (TAVR) with and without prosthesis-patient mismatch (PPM). METHODS AND RESULTS In a retrospective study, speckle-tracking echocardiography was used to(More)
BACKGROUND Although it is known that Anderson-Fabry Disease (AFD) can mimic the morphologic manifestations of hypertrophic cardiomyopathy (HCM) on echocardiography, there is a lack of cardiovascular magnetic resonance (CMR) literature on this. There is limited information in the published literature on the distribution of myocardial fibrosis in patients(More)