Learn More
Structural and compositional features of bacterial cell samples and of lipopolysaccharide±protein complex isolated from the cell surface of the plant-growth-promoting rhizobacterium Azospirillum brasilense (wild-type strain Sp7) were characterised using Fourier transform (FT) Raman spectroscopy. The structural spectroscopic information obtained is analysed(More)
Structural and compositional features of whole cells of the plant-growth-promoting rhizobacterium Azospirillum brasilense Sp7 under standard and heavy metal-stressed conditions are analysed using Fourier transform infrared (FTIR) spectroscopy and compared with the FT-Raman spectroscopic data obtained previously [J. Mol. Struct. 563±564 (2001) 199]. The(More)
Effects of exercise training on ␣-moto-neurons. Evidence is presented that one locus of adaptation in the " neural adaptations to training " is at the level of the ␣-motoneurons. With increased voluntary activity, these neurons show evidence of dendrite restructuring, increased protein synthesis, increased axon transport of proteins, enhanced neuromuscular(More)
Phenylketonuria (PKU) is caused by mutation(s) in the phenylalanine hydroxylase (PAH) gene which lead to deficient PAH activity and an accumulation of phenylalanine in the blood. The primary pathologic finding is hypomyelination and gliosis of central nervous system white matter. Similar white matter pathology is observed in the Pahenu2 mouse, a genetic(More)
The relative content of calcitonin gene-related peptide in lumbar motoneuron cell bodies (semiquantitative immunohistochemistry) and sciatic nerve was examined in rats who had previously undergone a 16-week period of endurance training on a motor-driven treadmill. Soleus motoneurons were identified in the spinal cord by their fluorescence following(More)
Fibrogenic growth factors can force epithelial cells of the lung, kidney and liver to undergo transition to a mesenchymal phenotype – a process known as epithelial to mesenchymal transition (EMT) 1. EMT contributes to fibrosis in these organs, and can be inhibited/reversed in animal models 2. EMT has not been shown in fibrotic skin disorders. We(More)
BACKGROUND AND PURPOSE Neutrophil serine proteases (NSPs) are activated by dipeptidyl peptidase 1 (DPP1) during neutrophil maturation. The effects of neutrophil turnover rate on NSP activity following DPP1 inhibition was studied in a rat pharmacokinetic/pharmacodynamic model. EXPERIMENTAL APPROACH Rats were treated with a DPP1 inhibitor twice daily for up(More)
2.15 pm The use of novel oral-anticoagulants in the prophylaxis of stroke in non-valvular atrial fibrillation. A review of prescribing practise and outcomes in the Belfast HSC Trust. 4.25 pm Learning from an uncommon cause of a common presentation – autoimmune encephalitis on the acute medical ward. 1. 1. Rheumatology department, Musgrave park hospital. 2.(More)