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Monoethylglycinexylidide (MEGX), the primary metabo-lite of lidocaine, is produced via oxidative N-deethylation catalyzed by cytochrome P450 (CYP) 3A4 (1). The MEGX test, a new dynamic test of liver function that assesses the rate of MEGX formation after a standard intravenous dose of lidocaine, is a highly sensitive indicator of hepatic dysfunction and has(More)
OBJECTIVES Diabetes negatively affects the outcome of patients undergoing percutaneous transluminal coronary angioplasty (PTCA) or coronary surgery. However, data are lacking with respect to the impact of arterial revascularization in the diabetic population. METHODS Between 1999 and 2003, 100 of 491 diabetics underwent coronary artery bypass graft(More)
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