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Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida albicans
TLDR
The different sensing and signaling pathways involved in the morphogenesis and pathogenesis of C. albicans are provided and the analogous pathways/genes in Saccharomyces cerevisiae are compared in an attempt to highlight the evolution of the different components of the two organisms. Expand
The Arabidopsis Trehalose-6-P Synthase AtTPS1 Gene Is a Regulator of Glucose, Abscisic Acid, and Stress Signaling1
TLDR
It is reported that overexpression of AtTPS1 in Arabidopsis using the 35S promoter led to a small increase in Trehalose and trehalose-6-P levels, which strongly suggest that AtTPS 1 has a pivotal role in the regulation of Glc and ABA signaling during vegetative development. Expand
On the safety of Aspergillus niger – a review
TLDR
It is concluded that A. niger is a safe production organism and new and unknown isolates should be checked for ochratoxin A production before they are developed as production organisms. Expand
An unexpected plethora of trehalose biosynthesis genes in Arabidopsis thaliana.
TLDR
A family of 11 TPS genes in Arabidopsis thaliana is uncovered, one of which encodes a trehalose-6-phosphate (Tre6P) synthase, and a subfamily of which might encode the still elusive Tre6P phosphatases. Expand
A Saccharomyces cerevisiae G‐protein coupled receptor, Gpr1, is specifically required for glucose activation of the cAMP pathway during the transition to growth on glucose
TLDR
It is shown that the G‐protein coupled receptor Gpr1 interacts with Gpa2 and is required for stimulation of cAMP synthesis by glucose, which appears to be the first example of a GPCR system activated by a nutrient in eukaryotic cells, suggesting a subfamily of GPCRs might be involved in nutrient sensing. Expand
Parameters Affecting Ethyl Ester Production by Saccharomyces cerevisiae during Fermentation
TLDR
The hypothesis that precursor availability has an important role in ethyl ester production is supported and the expression level and activity of the fatty acid biosynthetic enzymes appear to be prime targets for flavor modification by alteration of process parameters or through strain selection. Expand
The G protein-coupled receptor Gpr1 and the Galpha protein Gpa2 act through the cAMP-protein kinase A pathway to induce morphogenesis in Candida albicans.
TLDR
Results indicate that CaGpr1 functions upstream in the cAMP-protein kinase A (PKA) pathway, and show that, in the presence of glucose, CaGPR1 is important for amino acid-induced transition from yeast to hyphal cells. Expand
The Saccharomyces cerevisiae EHT1 and EEB1 Genes Encode Novel Enzymes with Medium-chain Fatty Acid Ethyl Ester Synthesis and Hydrolysis Capacity*
TLDR
The results identify Eht1 and Eeb1 as novel acyl-coenzymeA:ethanol O-acyltransferases/esterases, whereas the third family member, Ymr210w, does not seem to play an important role in medium-chain fatty acid ethyl ester formation. Expand
Trehalose is required for the acquisition of tolerance to a variety of stresses in the filamentous fungus Aspergillus nidulans.
TLDR
Interestingly, tpsA transcription is not induced in response to heat shock or during conidiation, indicating that trehalose accumulation is probably due to a post-translational activation process of the tre Halose 6-phosphate synthase. Expand
The PDE1-encoded low-affinity phosphodiesterase in the yeast Saccharomyces cerevisiae has a specific function in controlling agonist-induced cAMP signaling.
TLDR
The results suggest that serine252 might be the first target site for feedback inhibition of cAMP accumulation by PKA, and show that Pde1 is rapidly phosphorylated in vivo upon addition of glucose to glycerol-grown cells, and this activation is absent in the P de1(ala252) mutant. Expand
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