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Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida albicans
- Subhrajit Biswas, P. van Dijck, A. Datta
- BiologyMicrobiology and Molecular Biology Reviews
- 1 June 2007
The different sensing and signaling pathways involved in the morphogenesis and pathogenesis of C. albicans are provided and the analogous pathways/genes in Saccharomyces cerevisiae are compared in an attempt to highlight the evolution of the different components of the two organisms.
The Arabidopsis Trehalose-6-P Synthase AtTPS1 Gene Is a Regulator of Glucose, Abscisic Acid, and Stress Signaling1
- N. Avonce, B. Leyman, J. Mascorro-Gallardo, P. van Dijck, J. Thevelein, G. Iturriaga
- Environmental SciencePlant Physiology
- 1 November 2004
It is reported that overexpression of AtTPS1 in Arabidopsis using the 35S promoter led to a small increase in Trehalose and trehalose-6-P levels, which strongly suggest that AtTPS 1 has a pivotal role in the regulation of Glc and ABA signaling during vegetative development.
An unexpected plethora of trehalose biosynthesis genes in Arabidopsis thaliana.
On the safety of Aspergillus niger – a review
- E. Schuster, N. Dunn-Coleman, J. Frisvad, P. van Dijck
- BiologyApplied Microbiology and Biotechnology
It is concluded that A. niger is a safe production organism and new and unknown isolates should be checked for ochratoxin A production before they are developed as production organisms.
Parameters Affecting Ethyl Ester Production by Saccharomyces cerevisiae during Fermentation
- S. Saerens, F. Delvaux, K. Verstrepen, P. van Dijck, J. Thevelein, F. Delvaux
- Chemistry, MedicineApplied and Environmental Microbiology
- 9 November 2007
The hypothesis that precursor availability has an important role in ethyl ester production is supported and the expression level and activity of the fatty acid biosynthetic enzymes appear to be prime targets for flavor modification by alteration of process parameters or through strain selection.
A Saccharomyces cerevisiae G‐protein coupled receptor, Gpr1, is specifically required for glucose activation of the cAMP pathway during the transition to growth on glucose
It is shown that the G‐protein coupled receptor Gpr1 interacts with Gpa2 and is required for stimulation of cAMP synthesis by glucose, which appears to be the first example of a GPCR system activated by a nutrient in eukaryotic cells, suggesting a subfamily of GPCRs might be involved in nutrient sensing.
The G protein-coupled receptor Gpr1 and the Galpha protein Gpa2 act through the cAMP-protein kinase A pathway to induce morphogenesis in Candida albicans.
Results indicate that CaGpr1 functions upstream in the cAMP-protein kinase A (PKA) pathway, and show that, in the presence of glucose, CaGPR1 is important for amino acid-induced transition from yeast to hyphal cells.
The Saccharomyces cerevisiae EHT1 and EEB1 Genes Encode Novel Enzymes with Medium-chain Fatty Acid Ethyl Ester Synthesis and Hydrolysis Capacity*
The results identify Eht1 and Eeb1 as novel acyl-coenzymeA:ethanol O-acyltransferases/esterases, whereas the third family member, Ymr210w, does not seem to play an important role in medium-chain fatty acid ethyl ester formation.
Trehalose is required for the acquisition of tolerance to a variety of stresses in the filamentous fungus Aspergillus nidulans.
Interestingly, tpsA transcription is not induced in response to heat shock or during conidiation, indicating that trehalose accumulation is probably due to a post-translational activation process of the tre Halose 6-phosphate synthase.
A single active trehalose-6-P synthase (TPS) and a family of putative regulatory TPS-like proteins in Arabidopsis.
- L. Vandesteene, Matthew Ramon, Katrien Le Roy, P. van Dijck, F. Rolland
- BiologyMolecular Plant
- 1 March 2010
Evidence that Arabidopsis encodes a single trehalose-6-P synthase (TPS) next to a family of catalytically inactive TPS-like proteins that might fulfill specific regulatory functions in actively growing tissues is provided.