• Publications
  • Influence
Technology of mammalian cell encapsulation.
Entrapment of mammalian cells in physical membranes has been practiced since the early 1950s when it was originally introduced as a basic research tool. The method has since been developed based onExpand
  • 584
  • 18
  • PDF
History, challenges and perspectives of cell microencapsulation.
Cell microencapsulation continues to hold significant promise for biotechnology and medicine. The controlled, and continuous, delivery of therapeutic products to the host by immunoisolated cells is aExpand
  • 318
  • 10
  • PDF
Identification of Genetic Loci in Lactobacillus plantarum That Modulate the Immune Response of Dendritic Cells Using Comparative Genome Hybridization
Background Probiotics can be used to stimulate or regulate epithelial and immune cells of the intestinal mucosa and generate beneficial mucosal immunomodulatory effects. Beneficial effects ofExpand
  • 164
  • 10
  • PDF
Butyrate and other short-chain fatty acids as modulators of immunity: what relevance for health?
Purpose of reviewHigh-fiber diets have been shown to reduce plasma concentrations of inflammation markers. Increased production of fermentation-derived short-chain fatty acids (SCFAs) is one of theExpand
  • 290
  • 9
  • PDF
Alginate-based microcapsules for immunoisolation of pancreatic islets.
Transplantation of microencapsulated cells is proposed as a therapy for the treatment of a wide variety of diseases since it allows for transplantation of endocrine cells in the absence of undesiredExpand
  • 397
  • 8
  • PDF
Monocytes and Macrophages in Pregnancy and Pre-Eclampsia
Preeclampsia is an important complication in pregnancy, characterized by hypertension and proteinuria in the second half of pregnancy. Generalized activation of the inflammatory response is thoughtExpand
  • 256
  • 8
  • PDF
The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression.
The ob gene product, leptin, apparently exclusively expressed in adipose tissue, is a signaling factor regulating body weight homeostasis and energy balance. ob gene expression is increased in obeseExpand
  • 168
  • 8
  • PDF
Effects of Brain Death and Hemodynamic Status on Function and Immunologic Activation of the Potential Donor Liver in the Rat
ObjectiveTo assess the effect on the function and immunologic status of potential donor livers of the duration of brain death combined with the presence and absence of hemodynamic instability in theExpand
  • 143
  • 6
Recovery from hemophilia B Leyden: an androgen-responsive element in the factor IX promoter.
One form of the inherited, X-linked, bleeding disorder, hemophilia B, resolves after puberty. Mutations at -20 and -26 in the clotting factor IX promoter impair transcription by disrupting theExpand
  • 127
  • 6
Encapsulation of pancreatic islets for transplantation in diabetes: the untouchable islets.
The aim of encapsulation of pancreatic islets is to transplant in the absence of immunosuppression. It is based on the principle that transplanted tissue is protected from the host immune system byExpand
  • 121
  • 6
  • PDF